High blood pressure and high cholesterol, especially if you have them before turning 55, can raise your risk of heart disease, even if you work on improving these conditions later in life. These findings come from a study published in the journal PLOS ONE.
The researchers looked at data from the UK Biobank and divided the participants into three groups:
The researchers observed that if high LDL-C (bad cholesterol) and SBP (systolic blood pressure) levels could be predicted based on genetics, the risk of coronary heart disease increased, regardless of when these conditions were diagnosed.
They also found that individuals with high SBP and LDL-C levels in their younger years had a greater risk of coronary heart disease, regardless of their levels in later life. This suggests that the impact of these risk factors accumulates over time and has long-lasting effects on heart disease risk.
Furthermore, the study noted that the influence of SBP on coronary heart disease risk decreased with age, possibly because genetic factors have less impact as people age.
In discussing their findings, the researchers mentioned that their results align with previous studies indicating that medications like blood pressure drugs and statins can be beneficial even in older age. However, they pointed out that the use of these medications tends to decline as people get older.
In conclusion, the researchers emphasised the importance of treating young individuals with high SBP and LDL-C levels to minimise their risk of heart disease over their lifetime. They noted that age alone should not deter appropriate treatments for these risk factors, as their impact on heart disease risk remains consistent throughout life.
The study reaffirms that high blood pressure and elevated cholesterol are known risk factors for heart disease. This research, conducted over an extended period, helps us better understand how these factors impact people of different ages.
The findings won't change how healthcare providers typically treat patients. Hypertension and high cholesterol are already addressed throughout a person's life, especially in those under 55.
However, the study may encourage healthcare providers to manage cholesterol in younger patients proactively. Engaging with more youthful individuals to discuss risks and lifestyle changes for lowering cholesterol levels could become a more focused approach.
As people age, other factors like smoking, sedentary lifestyles, and poor dietary habits become more critical in heart disease risk. Therefore, modifying these factors remains crucial for reducing the risk, particularly for those with a history of high cholesterol, as the study indicates that persistent high cholesterol over time increases the risk of heart disease.
The study is considered reliable due to its large participant pool from the UK Biobank. Nonetheless, it had some limitations, such as variations in blood pressure and cholesterol medication use among different age groups. To address this, the researchers adjusted the data based on treatment status.
Experts emphasise that lifestyle choices play a significant role in the development of both high cholesterol and high blood pressure.
The Centers for Disease Control and Prevention (CDC) identifies specific risk factors for high blood pressure, including:
The CDC also lists risk factors for high cholesterol, which include:
Notably, poor diet, obesity, physical inactivity, and smoking are common factors found on both lists. Consult Mobi Doctor for expert medical advice and support if you need assistance.