← European Medicine Shortage Tracker

Medicine shortages in Germany 🇩🇪 — Lieferengpass

Availability information only — Mobi Doctor doesn't sell medicines; check with a pharmacy.

MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

226 medicines currently affected according to BfArM (Germany) · updated 21 September 2026

Shortage 483

Key facts

483 product-level reports are open, 35 of them newly filed in September 2026. Where the register states a cause, the leading ones are manufacturing problems (252), unexpectedly high demand (126) out of 378 reports with a stated cause. The longest-running open case is Hydrochlorothiazid; Valsartan, reported on 2018-07-01 — about 98 months ago.

How to read this register: BfArM logs company-reported Lieferengpässe per product, flags hospital-relevant cases, and usually names an alternative product — one medicine can appear once per strength.

How medicine shortages are managed in Germany

Pharmaceutical companies report supply interruptions of prescription medicines to BfArM, which publishes them in the register this page tracks.

A standing advisory board (Beirat) at BfArM reviews the list and classifies which shortages are supply-critical (versorgungskritisch); those get active management — data requests, stock monitoring, and coordination with hospitals and wholesalers.

Since the 2023 ALBVVG supply law, pharmacies may deviate from the prescribed pack size, strength or dosage form of the same active substance during a listed shortage without sending the patient back to the prescriber — a flexibility made permanent after the pandemic.

If the health ministry formally declares a Versorgungsmangel (supply emergency), temporary imports of foreign-labelled packs become permissible for that medicine.

Structurally, Germany's rebate-contract system concentrates generic supply on few winners per substance, which is why a single manufacturing problem can empty the market — a dynamic the ALBVVG tries to soften for antibiotics and children's medicines.

What to do if your medicine is affected in Germany

If your medicine appears here, ask your Apotheke first: German rules give pharmacies extra substitution flexibility during declared shortages, and BfArM's register usually names an alternative product (see the Alternatives column). For hospital-relevant medicines, supplies are actively managed. Your prescriber can switch you to a listed equivalent where one exists. Never stop a treatment on your own — confirm any switch with your pharmacist or prescriber.

Searched locally as: Lieferengpass, Lieferengpässe, Medikament nicht lieferbar.

Newest reports

MedicineStatusReportedExpected end
EsmololShortage2027-05-012027-12-31
EncorafenibShortage2026-11-022026-11-15
Methyldopa (Ph.Eur.)Shortage2026-10-302026-12-18
Midodrine hydrochlorideShortage2026-10-272026-12-02
Olipudase alfaShortage2026-10-262026-12-31
EncorafenibShortage2026-10-052026-11-15
Olanzapinembonat-MonohydratShortage2026-09-292026-11-25
RasburicaseShortage2026-09-292026-10-21
BinimetinibShortage2026-09-282026-10-25
Dexamethasondihydrogenphosphat-Dinatrium (Ph.Eur.)Shortage2026-09-212026-12-31

All affected medicines

MedicineStatusSince Expected endReports
Hydrochlorothiazid; ValsartanShortage2018-07-012026-12-313
Cefixim 3 H<2>OShortage2018-10-012026-12-311
Fibrinogen vom MenschenShortage2019-05-012027-01-311
Natrium(hydrocortison-21-succinat)Shortage2019-07-012026-12-311
Flucloxacillin-Natrium 1 H<2>OShortage2020-08-012026-10-301
Eisen(III)-hexacyanoferrat(II)Shortage2021-02-242026-12-311
BCG-Bakterien, Stamm TICE, lebend, attenuiertShortage2021-03-012026-12-311
VerteporfinShortage2021-07-012026-12-311
PenicillaminShortage2022-03-202027-03-311
Bendamustinhydrochlorid-MonohydratShortage2022-05-012026-12-311
CalciumfolinatShortage2022-05-062028-09-152
SomatostatinacetatShortage2022-12-092026-12-311
Rosuvastatin-HemicalciumShortage2023-03-062027-07-317
AlprostadilShortage2023-03-162028-01-153
MelperonhydrochloridShortage2023-03-242026-12-312
Desogestrel; EthinylestradiolShortage2023-03-312026-12-311
VindesineShortage2023-10-232026-11-301
GemcitabinhydrochloridShortage2023-12-042027-01-311
AdenosineShortage2024-03-012027-12-313
Isosorbid-5-mononitratShortage2024-04-082026-10-266
Amoxicillin-TrihydratShortage2024-05-012026-12-011
FluconazolShortage2024-06-012026-12-311
TerazosinShortage2024-07-012027-03-316
Quetiapinfumarat (Ph.Eur.)Shortage2024-07-232027-03-3144
AprepitantShortage2024-08-012026-12-305
Doxorubicin hydrochlorideShortage2024-08-162027-01-193
FluorometholonShortage2024-08-222026-10-311
RisperidoneShortage2024-09-052027-04-159
Calciumchlorid-Dihydrat; Histidin; Histidinhydrochlorid-Monohydrat; Kalium-hydrogen-2-oxopentandioat; Kaliumchlorid; Magnesiumchlorid-Hexahydrat; Mannitol (Ph.Eur.); Natriumchlorid; TryptophanShortage2024-09-182026-12-311
GalantaminaShortage2024-10-022027-12-3115
Levothyroxin-Natrium (Ph.Eur.)Shortage2024-11-012026-12-312
Mannitol (Ph.Eur.)Shortage2024-11-012026-11-301
DarifenacinhydrobromidShortage2024-11-042030-01-012
Fosfomycin-Natrium (Ph.Eur.)Shortage2024-11-052026-09-302
LevomepromazinhydrochloridShortage2024-11-152028-05-151
PrednisoloneShortage2024-11-212027-03-015
Methyldopa (Ph.Eur.)Shortage2024-12-022026-12-182
Liothyronin-NatriumShortage2024-12-022027-02-011
TeicoplaninShortage2024-12-182026-09-302
LevetiracetamShortage2025-01-012026-12-3111
ProcainhydrochloridShortage2025-01-102027-08-312
VancomycinhydrochloridShortage2025-01-152026-11-301
DistigminbromidShortage2025-01-302026-12-311
Candesartan cilexetilShortage2025-02-112028-10-055
TacrolimusShortage2025-02-152026-12-317
Pramipexoldihydrochlorid-MonohydratShortage2025-03-032026-09-301
Calciumacetat; Schweres, basisches MagnesiumcarbonatShortage2025-03-242027-03-311
Atorvastatin-Calcium-Trihydrat (Ph.Eur.)Shortage2025-03-282026-12-316
Natrium(methylprednisolon-21-succinat)Shortage2025-03-312027-06-305
Calciumchlorid-Dihydrat; Magnesiumchlorid-Hexahydrat; Natriumchlorid; NatriumhydrogencarbonatShortage2025-04-012027-04-011
SertralineShortage2025-04-142026-10-312
NifedipinShortage2025-04-152026-12-312
FlupentixoldecanoatShortage2025-04-302026-10-153
IpratropiumbromidShortage2025-05-012026-10-311
RibavirineShortage2025-05-022026-10-152
OxcarbazepinShortage2025-05-092026-11-301
Arsen(III)-oxidShortage2025-05-192026-09-241
EsomeprazoleShortage2025-05-222026-12-314
Insulin aspartShortage2025-05-312026-12-311
NitrendipineShortage2025-06-022026-12-311
BortezomibmannitolShortage2025-06-022026-10-151
Epoetin betaShortage2025-06-092027-06-304
(2-Aminoethyl)dihydrogenphosphat-Calciumsalz (1:1)Shortage2025-06-112026-12-181
TrospiumchloridShortage2025-06-112027-09-301
CiprofloxacinShortage2025-07-012026-09-301
Doxepinhydrochlorid (Ph.Eur.)Shortage2025-07-072026-12-313
PromethazinhydrochloridShortage2025-07-152028-07-151
Minocyclinhydrochlorid-Dihydrat (Ph.Eur.)Shortage2025-07-152026-11-021
Amlodipinbesilat; Perindopril-tert-butylaminShortage2025-07-162026-11-151
DinoprostoneShortage2025-07-212027-02-284
BudesonideShortage2025-08-012026-12-311
Beclometasondipropionat (Ph.Eur.)Shortage2025-08-012026-12-312
SalbutamolShortage2025-08-012026-12-312
Von Willebrand-FaktorShortage2025-08-012026-09-301
Phenytoin-NatriumShortage2025-08-192026-09-301
CalcitriolShortage2025-08-262026-12-313
Ezetimibe, SimvastatinShortage2025-09-012026-09-304
BesilesomabShortage2025-09-172028-06-261
TranexamsäureShortage2025-09-292027-03-301
CytarabinShortage2025-10-072027-12-314
UrapidilShortage2025-10-092026-11-156
IsotretinoinShortage2025-10-112026-12-318
VinorelbinaShortage2025-10-152026-12-311
FlutamidShortage2025-10-222026-12-011
EtanerceptShortage2025-10-272026-09-251
AdalimumabShortage2025-11-012026-09-251
Dexamethasonacetat (Ph.Eur.); Lidocainhydrochlorid-MonohydratShortage2025-11-012027-11-012
PropranololhydrochloridShortage2025-11-032026-10-314
MesalazineShortage2025-11-052026-10-301
Lanreotidacetat (1:x) ((mit Angaben zum Essigsäure-Gehalt))Shortage2025-11-092027-02-021
Tolterodine tartrateShortage2025-11-142028-01-031
MitomycineShortage2025-11-182027-02-011
TriamcinolonacetonidShortage2025-11-242026-11-204
BenperidolShortage2025-11-242028-03-151
Benzylpenicillin-Benzathin-Tetrahydrat (Ph.Eur.) ((mit Angaben zum Dispergier- oder Suspendiermittel))Shortage2025-11-242026-10-311
IvermectinShortage2025-11-282026-12-141
Cefaclor-MonohydratShortage2025-12-012026-09-302
EverolimusShortage2025-12-012026-10-011
MethantheliniumbromidShortage2025-12-012026-10-041
IsoniazidShortage2025-12-082026-10-191
Paliperidon palmitatShortage2025-12-092027-03-075
DinatriumpamidronatShortage2025-12-112026-09-301
Dexamethasondihydrogenphosphat-Dinatrium (Ph.Eur.)Shortage2025-12-152028-03-315
Nilotinibhydrochlorid-DihydratShortage2025-12-192026-10-051
IndométacineShortage2025-12-312026-09-301
TobramycineShortage2026-01-012026-09-301
BusulfanShortage2026-01-012026-10-211
CarmustineShortage2026-01-052026-12-311
ErythromycinlactobionatShortage2026-01-092026-09-301
CyclophosphamideShortage2026-01-212026-12-314
IfosfamideShortage2026-01-212027-12-315
AbirateronaShortage2026-01-212026-11-062
Duloxetine hydrochlorideShortage2026-01-232026-12-312
Pantoprazol-Natrium-SesquihydratShortage2026-02-012026-11-306
CrisantaspaseShortage2026-02-042026-12-311
DapsonShortage2026-02-092026-10-151
RitonavirShortage2026-02-122027-09-301
AciclovirShortage2026-02-162026-12-302
TelmisartanShortage2026-02-182026-10-061
Bisoprololfumarat (Ph.Eur.); HydrochlorothiazidShortage2026-02-192026-12-312
Acetylcystein; Alanin; Arginin; Glycin; Histidin; Isoleucin; L-Äpfelsäure; Leucin; Lysinacetat; Methionin; N-Acetyltyrosin (Ph.Eur.); Phenylalanin; Prolin; Serin; Taurin; Threonin; Tryptophan; ValinShortage2026-02-192026-12-311
Alanin; Arginin; Glycin; Histidin; Isoleucin; Leucin; Lysinacetat; Methionin; Phenylalanin; Prolin; Serin; Taurin; Threonin; Tryptophan; Tyrosin; ValinShortage2026-02-192026-12-311
Brimonidin tartratShortage2026-02-232026-10-051
EletriptanhydrobromidShortage2026-03-012026-12-313
GolimumabShortage2026-03-012027-05-031
ClomifencitratShortage2026-03-092026-10-131
ValsartanShortage2026-03-192026-12-312
SultiamShortage2026-03-192026-10-152
AmitriptylinhydrochloridShortage2026-03-262026-10-095
OlanzapineShortage2026-04-012026-12-316
PazopanibhydrochloridShortage2026-04-012026-10-121
CefuroximaxetilShortage2026-04-012026-11-132
Mittelkettige Triglyceride; Omega-3-Säuren-reiches Fischöl ((mit Angaben zur Zusammensetzung)); Raffiniertes Olivenöl; Raffiniertes Sojaöl (Ph.Eur.)Shortage2026-04-022026-10-301
ErythromycinestolatShortage2026-04-102027-06-301
Dabigatran etexilatoShortage2026-04-212026-12-153
(RS)-2,3-Bis(sulfanyl)propan-1-sulfonsäure-Natriumsalz-MonohydratShortage2026-04-222026-09-301
Acetylcystein; Alanin; Arginin; Essigsäure 99%; Glycin; Histidin; Isoleucin; Leucin; Lysinacetat; Methionin; Phenylalanin; Prolin; Serin; Threonin; Tryptophan; ValinShortage2026-04-222026-12-311
Acetylcystein; Alanin; Arginin; Glycin; Histidin; Isoleucin; Leucin; Lysinacetat; Methionin; N-Glycyl-L-tyrosin-Dihydrat; Phenylalanin; Prolin; Serin; Threonin; Tryptophan; Tyrosin; ValinShortage2026-04-222026-09-301
VoriconazoleShortage2026-04-232026-09-301
PhényléphrineShortage2026-04-272026-10-312
TopiramateShortage2026-05-012026-10-311
PropofolShortage2026-05-012026-12-312
Metoprololsuccinat (Ph.Eur.)Shortage2026-05-072026-11-301
DiltiazemhydrochloridShortage2026-05-112027-03-314
AcetylcholinchloridShortage2026-05-152027-01-151
FenofibratShortage2026-05-182026-09-211
IdarubicinhydrochloridShortage2026-05-192027-02-192
Fluorescein-Natrium (Ph.Eur.); OxybuprocainhydrochloridShortage2026-05-192026-11-161
IohexolShortage2026-05-222026-09-301
DorzolamidhydrochloridShortage2026-05-262026-10-301
FingolimodShortage2026-06-012026-11-042
CabergolineShortage2026-06-012026-10-162
Ampicillin-Natrium; Sulbactam-NatriumShortage2026-06-012028-03-311
DexamethasonShortage2026-06-012027-01-291
MelphalanhydrochloridShortage2026-06-052026-12-311
OxytocinShortage2026-06-082026-10-141
RizatriptanbenzoatShortage2026-06-102026-10-162
RivaroxabanShortage2026-06-152026-10-021
TeriflunomidShortage2026-06-152026-10-301
Amlodipinbesilat; Hydrochlorothiazid; ValsartanShortage2026-06-162026-12-311
CarbamazépineShortage2026-06-162026-12-151
Avibactam-Natrium; AztreonamShortage2026-06-172026-12-311
IbuprofenShortage2026-06-222026-09-301
EscitalopramShortage2026-06-222026-10-306
LevonorgestrelShortage2026-06-222026-12-312
EntecavirShortage2026-06-232026-12-313
Kanamycinmonosulfat (Ph.Eur.)Shortage2026-06-232026-12-311
PioglitazonhydrochloridShortage2026-06-302026-10-311
Cisatracurium BesilateShortage2026-06-302027-03-311
Gentamicin sulfateShortage2026-06-302026-09-301
Fluorescein-Natrium (Ph.Eur.)Shortage2026-06-302026-11-101
EtoricoxibShortage2026-07-012026-12-046
MesnaShortage2026-07-012026-10-311
Tirofibanhydrochlorid-MonohydratShortage2026-07-012026-10-151
Cefalexin-MonohydratShortage2026-07-012026-10-211
DigitoxinShortage2026-07-012027-01-291
Avalglucosidase alfaShortage2026-07-032026-09-301
Metoprololtartrat (Ph.Eur.)Shortage2026-07-042026-12-311
Sumatriptan succinateShortage2026-07-062026-10-301
TerbinafinhydrochloridShortage2026-07-062026-10-161
LanthanShortage2026-07-062027-03-153
Econazolnitrat; TriamcinolonacetonidShortage2026-07-072026-12-041
LiraglutideShortage2026-07-092027-03-311
PlerixaforShortage2026-07-152026-12-311
IodixanolShortage2026-07-202026-10-142
Olanzapinembonat-MonohydratShortage2026-07-222026-12-023
Dexamethasondihydrogenphosphat-Dinatrium (Ph.Eur.); GentamicinsulfatShortage2026-07-282026-10-311
Dinatrium-pentacyanonitrosylferrat(2-)Shortage2026-08-012026-10-311
NaproxenShortage2026-08-032026-10-061
RopivacainhydrochloridShortage2026-08-032026-11-243
Triamteren; XipamidShortage2026-08-052027-04-301
Trandolapril; VerapamilhydrochloridShortage2026-08-062026-11-161
Calcium, CholecalciferolShortage2026-08-102027-01-311
PrednicarbatShortage2026-08-102026-10-301
NatriumhydrogencarbonatShortage2026-08-112027-06-152
ClarithromycinlactobionatShortage2026-08-122026-09-301
TropicamideShortage2026-08-172026-09-212
HydrocortisonShortage2026-08-172026-10-111
PalonosetronhydrochloridShortage2026-08-172026-10-071
Levothyroxine sodiumShortage2026-08-192026-10-072
Fludarabinphosphat (Ph.Eur.)Shortage2026-08-202026-12-311
Moxifloxacinhydrochlorid (Ph.Eur.) ((mit Angaben zum Wasser-Gehalt (1:x)))Shortage2026-08-252026-10-091
Pankreas-Pulver vom SchweinShortage2026-08-252026-12-011
RifampicineShortage2026-08-262026-10-194
MivacuriumchloridShortage2026-08-262026-11-301
Natriumcromoglicat (Ph.Eur.); ReproterolhydrochloridShortage2026-08-272027-03-011
Perindopril tosilate, IndapamideShortage2026-08-282026-12-151
Lidocain; PrilocainShortage2026-08-312026-12-311
CefotaximeShortage2026-09-012026-11-302
AmiodaronhydrochloridShortage2026-09-012026-11-231
Vinfluninbis[(R,R)-tartrat]Shortage2026-09-012027-05-011
CilostazolShortage2026-09-022026-09-301
PosaconazolShortage2026-09-022026-10-301
TrofosfamidShortage2026-09-032026-11-201
AmisulpridShortage2026-09-072026-10-161
Indapamid; Perindopril-tert-butylaminShortage2026-09-112026-11-161
Anti-Human-T-Lymphozyten-Immunglobulin vom PferdShortage2026-09-152026-11-301
ValganciclovirhydrochloridShortage2026-09-172026-12-011
GlucagonShortage2026-09-212026-11-271
OfloxacinShortage2026-09-212026-10-301
BinimetinibShortage2026-09-282026-10-251
RasburicaseShortage2026-09-292026-10-211
EncorafenibShortage2026-10-052026-11-152
Olipudase alfaShortage2026-10-262026-12-311
Midodrine hydrochlorideShortage2026-10-272026-12-021
EsmololShortage2027-05-012027-12-311

Shortages by country

Every row links to the medicine's Europe-wide page; statuses come from the official register linked above and can change daily. Not medical advice.

Frequently asked

How many medicines are currently in shortage in Germany?

As of 21 September 2026, 226 medicines have open availability reports in BfArM (Germany), covering 483 product-level entries. 35 new reports were filed in September 2026.

Where does Germany publish its official shortage list?

BfArM (Germany) — this page aggregates it daily and links every entry back to the official record. BfArM logs company-reported Lieferengpässe per product, flags hospital-relevant cases, and usually names an alternative product — one medicine can appear once per strength.

Can a German pharmacy give me a substitute without a new prescription?

Within limits, yes. During a listed Lieferengpass, pharmacies may hand out a different pack size, strength or dosage form of the same active substance without a new prescription. A switch to a different active substance still needs your prescriber — BfArM's register usually names candidate alternatives.

Why does Germany have so many medicine shortages?

Most stated causes in the register are production problems and increased demand, but the structural driver is economic: rebate tenders concentrate each generic on very few suppliers, and much active-ingredient production sits outside Europe. When one plant fails, there is often no second source serving the German market.

Embed this counter

Newsrooms and health sites may embed the live Germany shortage count — free, with attribution:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/country/de/embed.html" width="100%" height="130" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Medicine shortages in Germany"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/country/de/">Medicine shortages in Germany — European Medicine Shortage Tracker</a> by MobiDoctor</p>