← European Medicine Shortage Tracker

Medicine shortages in Germany 🇩🇪 — Lieferengpass

225 medicines currently affected according to BfArM (Germany) · updated 7 August 2026

MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027
Shortage 496

Key facts

496 product-level reports are open, 12 of them newly filed in August 2026. Where the register states a cause, the leading ones are manufacturing problems (265), unexpectedly high demand (119) out of 384 reports with a stated cause. The longest-running open case is Hydrochlorothiazid; Valsartan, reported on 2018-07-01 — about 97 months ago.

How to read this register: BfArM logs company-reported Lieferengpässe per product, flags hospital-relevant cases, and usually names an alternative product — one medicine can appear once per strength.

How medicine shortages are managed in Germany

Pharmaceutical companies report supply interruptions of prescription medicines to BfArM, which publishes them in the register this page tracks.

A standing advisory board (Beirat) at BfArM reviews the list and classifies which shortages are supply-critical (versorgungskritisch); those get active management — data requests, stock monitoring, and coordination with hospitals and wholesalers.

Since the 2023 ALBVVG supply law, pharmacies may deviate from the prescribed pack size, strength or dosage form of the same active substance during a listed shortage without sending the patient back to the prescriber — a flexibility made permanent after the pandemic.

If the health ministry formally declares a Versorgungsmangel (supply emergency), temporary imports of foreign-labelled packs become permissible for that medicine.

Structurally, Germany's rebate-contract system concentrates generic supply on few winners per substance, which is why a single manufacturing problem can empty the market — a dynamic the ALBVVG tries to soften for antibiotics and children's medicines.

What to do if your medicine is affected in Germany

If your medicine appears here, ask your Apotheke first: German rules give pharmacies extra substitution flexibility during declared shortages, and BfArM's register usually names an alternative product (see the Alternatives column). For hospital-relevant medicines, supplies are actively managed. Your prescriber can switch you to a listed equivalent where one exists. Never stop a treatment on your own — confirm any switch with your pharmacist or prescriber.

Searched locally as: Lieferengpass, Lieferengpässe, Medikament nicht lieferbar.

Newest reports

MedicineStatusReportedExpected end
EsmololhydrochloridShortage2027-05-012027-12-31
Midodrine hydrochlorideShortage2026-10-272026-12-02
CefotaximeShortage2026-09-012026-11-30
CefotaximeShortage2026-09-012026-11-30
Vinfluninbis[(R,R)-tartrat]Shortage2026-09-012027-05-01
Olanzapinembonat-MonohydratShortage2026-08-262026-11-10
Fludarabinphosphat (Ph.Eur.)Shortage2026-08-202026-12-31
Olanzapinembonat-MonohydratShortage2026-08-162026-11-25
Calcium, CholecalciferolShortage2026-08-102027-01-31
Iobenguan ((123)I)Shortage2026-08-102026-08-28

All affected medicines

MedicineStatusSince Expected endReports
Hydrochlorothiazid; ValsartanShortage2018-07-012026-12-313
Cefixim 3 H<2>OShortage2018-10-012026-12-311
Fibrinogen vom MenschenShortage2019-05-012027-01-311
Natrium(hydrocortison-21-succinat)Shortage2019-07-012026-12-311
Flucloxacillin-Natrium 1 H<2>OShortage2020-08-012026-09-141
Eisen(III)-hexacyanoferrat(II)Shortage2021-02-242026-12-311
BCG-Bakterien, Stamm TICE, lebend, attenuiertShortage2021-03-012026-12-311
VerteporfinShortage2021-07-012026-12-311
PenicillaminShortage2022-03-202027-03-311
Bendamustinhydrochlorid-MonohydratShortage2022-05-012026-12-311
Kalciumfolinat hydratShortage2022-05-062028-09-152
SomatostatinacetatShortage2022-12-092026-12-311
Rosuvastatin-HemicalciumShortage2023-03-062027-07-317
AlprostadilShortage2023-03-162028-01-153
MelperonhydrochloridShortage2023-03-242026-12-312
Desogestrel, etinylestradiolShortage2023-03-312026-12-311
PrednisoloneShortage2023-05-252027-03-015
Codeinphosphat-Hemihydrat; Coffein; ParacetamolShortage2023-08-162026-12-301
VindesineShortage2023-10-232026-09-301
CinacalcetShortage2023-11-102026-09-221
GemcitabinhydrochloridShortage2023-12-042027-01-311
AdenosineShortage2024-03-012027-12-313
BuprenorfinShortage2024-03-132026-11-245
Isosorbid-5-mononitratShortage2024-04-082026-10-266
Amoxicillin-TrihydratShortage2024-05-012026-08-271
Atomoxetine hydrochlorideShortage2024-05-032026-09-3014
FluconazolShortage2024-06-012026-12-311
TerazosinShortage2024-07-012026-12-316
Quetiapinfumarat (Ph.Eur.)Shortage2024-07-232027-03-3143
AprepitantShortage2024-08-012026-12-307
Doxorubicin hydrochlorideShortage2024-08-162027-01-193
FluorometholonShortage2024-08-222026-10-311
Hydromorphone hydrochlorideShortage2024-09-022027-03-316
RisperidoneShortage2024-09-052027-04-159
Calciumchlorid-Dihydrat; Histidin; Histidinhydrochlorid-Monohydrat; Kalium-hydrogen-2-oxopentandioat; Kaliumchlorid; Magnesiumchlorid-Hexahydrat; Mannitol (Ph.Eur.); Natriumchlorid; TryptophanShortage2024-09-182026-12-311
GalantaminaShortage2024-10-022027-12-3114
OxazepamShortage2024-10-312026-09-301
Levothyroxin-Natrium (Ph.Eur.)Shortage2024-11-012026-12-312
Mannitol (Ph.Eur.)Shortage2024-11-012026-11-301
DarifenacinhydrobromidShortage2024-11-042030-01-012
Fosfomycin-Natrium (Ph.Eur.)Shortage2024-11-052026-09-302
LevomepromazinhydrochloridShortage2024-11-152028-05-151
Levothyroxin-Natrium x H<2>OShortage2024-12-022027-02-011
Liothyronin-NatriumShortage2024-12-022027-02-011
Methyldopa (Ph.Eur.)Shortage2024-12-022026-08-311
TeicoplaninShortage2024-12-182026-09-302
LevetiracetamShortage2025-01-012026-12-3110
ProcainhydrochloridShortage2025-01-102027-08-312
VancomycinhydrochloridShortage2025-01-152026-11-301
DistigminbromidShortage2025-01-302026-12-311
Candesartan cilexetilShortage2025-02-112028-10-055
Tacrolimus-MonohydratShortage2025-02-152026-12-316
Pramipexoldihydrochlorid-MonohydratShortage2025-03-032026-09-302
Calciumacetat; Schweres, basisches MagnesiumcarbonatShortage2025-03-242027-03-311
Atorvastatin-Calcium-Trihydrat (Ph.Eur.)Shortage2025-03-282026-12-317
Natrium(methylprednisolon-21-succinat)Shortage2025-03-312027-06-305
Calciumchlorid-Dihydrat; Magnesiumchlorid-Hexahydrat; Natriumchlorid; NatriumhydrogencarbonatShortage2025-04-012027-04-011
SertralineShortage2025-04-142026-08-312
NifedipinShortage2025-04-152026-12-312
EzetimibeShortage2025-04-222026-09-041
FlupentixoldecanoatShortage2025-04-302026-09-153
Ipratropiumbromid (monohydrat)Shortage2025-05-012026-10-311
RibavirineShortage2025-05-022026-10-152
OxcarbazepinShortage2025-05-092026-09-301
Arsen(III)-oxidShortage2025-05-192026-09-011
EsomeprazoleShortage2025-05-222026-12-314
Insulin aspartShortage2025-05-312026-12-311
NitrendipineShortage2025-06-022026-12-312
BortezomibmannitolShortage2025-06-022026-11-301
Epoetin betaShortage2025-06-092027-06-304
(2-Aminoethyl)dihydrogenphosphat-Calciumsalz (1:1)Shortage2025-06-112026-12-181
TrospiumchloridShortage2025-06-112027-09-301
CiprofloxacinShortage2025-07-012026-08-314
GabapentinShortage2025-07-042026-12-316
Doxepinhydrochlorid (Ph.Eur.)Shortage2025-07-072026-12-313
PromethazinhydrochloridShortage2025-07-152028-07-151
Minocyclinhydrochlorid-Dihydrat (Ph.Eur.)Shortage2025-07-152026-11-021
Amlodipinbesilat; Perindopril-tert-butylaminShortage2025-07-162026-11-151
DinoprostoneShortage2025-07-212026-10-314
BudesonideShortage2025-08-012026-12-311
SalbutamolShortage2025-08-012026-12-312
Beclometasondipropionat (Ph.Eur.)Shortage2025-08-012026-12-312
Von Willebrand-FaktorShortage2025-08-012026-09-301
FluoxetinhydrochloridShortage2025-08-062026-08-071
Phenytoin-NatriumShortage2025-08-192026-09-301
CalcitriolShortage2025-08-262026-12-314
Ezetimibe, SimvastatinShortage2025-09-012026-08-314
ClonidinhydrochloridShortage2025-09-012026-08-241
BesilesomabShortage2025-09-172028-06-261
TranexamsäureShortage2025-09-292027-03-301
CytarabinShortage2025-10-072027-01-113
UrapidilShortage2025-10-092026-10-314
IsotretinoinShortage2025-10-112026-12-316
VinorelbinaShortage2025-10-152026-12-311
FlutamidShortage2025-10-222026-08-311
EtanerceptShortage2025-10-272026-08-311
AdalimumabShortage2025-11-012026-09-252
Dexamethasonacetat (Ph.Eur.); Lidocainhydrochlorid-MonohydratShortage2025-11-012027-11-012
PropranololhydrochloridShortage2025-11-032026-10-315
MesalazineShortage2025-11-052026-10-301
Lanreotidacetat (1:x) ((mit Angaben zum Essigsäure-Gehalt))Shortage2025-11-092027-02-021
Tolterodine tartrateShortage2025-11-142028-01-032
MitomycineShortage2025-11-182027-02-011
MivacuriumchloridShortage2025-11-202026-09-301
TriamcinolonacetonidShortage2025-11-242026-10-183
BenperidolShortage2025-11-242028-03-151
Benzylpenicillin-Benzathin-Tetrahydrat (Ph.Eur.) ((mit Angaben zum Dispergier- oder Suspendiermittel))Shortage2025-11-242026-10-311
IvermektinShortage2025-11-282026-12-141
Cefaclor-MonohydratShortage2025-12-012026-08-312
MethantheliniumbromidShortage2025-12-012026-10-041
IsoniazidShortage2025-12-082026-08-311
Paliperidon palmitatShortage2025-12-092027-03-075
DinatriumpamidronatShortage2025-12-112026-09-301
Dexamethasondihydrogenphosphat-Dinatrium (Ph.Eur.)Shortage2025-12-152028-03-315
IndometacinShortage2025-12-312026-08-261
TobramycineShortage2026-01-012026-08-311
BusulfanShortage2026-01-012026-08-151
CarmustineShortage2026-01-052026-12-311
ErythromycinlactobionatShortage2026-01-092026-09-301
CyclophosphamideShortage2026-01-212026-12-313
IfosfamideShortage2026-01-212026-12-311
AbirateronaShortage2026-01-212026-08-142
Duloxetine hydrochlorideShortage2026-01-232026-12-312
Pantoprazol-Natrium-SesquihydratShortage2026-02-012026-11-306
CrisantaspaseShortage2026-02-042026-12-311
DapsonShortage2026-02-092026-08-071
RitonavirShortage2026-02-122027-03-311
MethylprednisoloneShortage2026-02-132027-01-291
Amidotrizoatmeglumin, natriumamidotrizoatShortage2026-02-132026-12-311
AciklovirShortage2026-02-162026-09-302
FlurazepamShortage2026-02-162026-09-281
TelmisartanShortage2026-02-182026-08-141
Bisoprololfumarat (Ph.Eur.); HydrochlorothiazidShortage2026-02-192026-10-312
Brimonidin tartratShortage2026-02-232026-08-201
EletriptanhydrobromidShortage2026-03-012026-12-311
Tirofibanhydrochlorid-MonohydratShortage2026-03-022026-08-311
FenoterolhydrobromidShortage2026-03-022026-09-041
ClomifencitratShortage2026-03-092026-09-151
TemazepamShortage2026-03-162026-08-182
ValsartanShortage2026-03-192026-12-312
SultiamShortage2026-03-192026-10-152
RifabutinShortage2026-03-202026-10-311
AmitriptylinhydrochloridShortage2026-03-262026-10-016
Moxifloxacinhydrochlorid (Ph.Eur.) ((mit Angaben zum Wasser-Gehalt (1:x)))Shortage2026-03-262026-08-311
OlanzapineShortage2026-04-012026-12-314
PazopanibhydrochloridShortage2026-04-012026-09-153
CefuroximaxetilShortage2026-04-012026-08-311
ReproterolhydrochloridShortage2026-04-012026-08-211
FampridinShortage2026-04-022026-08-131
Mittelkettige Triglyceride; Omega-3-Säuren-reiches Fischöl ((mit Angaben zur Zusammensetzung)); Raffiniertes Olivenöl; Raffiniertes Sojaöl (Ph.Eur.)Shortage2026-04-022026-08-311
ErythromycinestolatShortage2026-04-102027-06-301
Dabigatran etexilatoShortage2026-04-212026-12-153
(RS)-2,3-Bis(sulfanyl)propan-1-sulfonsäure-Natriumsalz-MonohydratShortage2026-04-222026-09-301
VoriconazoleShortage2026-04-232026-08-141
PhényléphrineShortage2026-04-272026-10-312
IodixanolShortage2026-04-272026-10-152
RizatriptanbenzoatShortage2026-04-302026-11-304
TopiramateShortage2026-05-012026-09-072
PropofolShortage2026-05-012026-12-312
Metoprololsuccinat (Ph.Eur.)Shortage2026-05-072026-08-311
DiltiazemhydrochloridShortage2026-05-112027-03-314
SunitinibShortage2026-05-122026-08-181
AcetylcholinchloridShortage2026-05-152026-10-301
FenofibratShortage2026-05-182026-09-031
IdarubicinhydrochloridShortage2026-05-192027-02-192
Fluorescein-Natrium (Ph.Eur.); OxybuprocainhydrochloridShortage2026-05-192026-09-031
IohexolShortage2026-05-222026-08-271
DorzolamidhydrochloridShortage2026-05-262026-10-301
FingolimodShortage2026-06-012026-09-301
CabergolineShortage2026-06-012026-08-312
DexamethasonShortage2026-06-012027-01-291
Ampicillin-Natrium; Sulbactam-NatriumShortage2026-06-012028-03-311
Hydrocortisonacetat (Ph.Eur.)Shortage2026-06-052026-08-311
MelphalanhydrochloridShortage2026-06-052026-12-311
Hydrochlorothiazid; RamiprilShortage2026-06-082026-08-211
OxytocinShortage2026-06-082026-10-141
RivaroxabanShortage2026-06-152026-12-311
TeriflunomidShortage2026-06-152026-10-301
Amlodipinbesilat; Hydrochlorothiazid; ValsartanShortage2026-06-162026-12-311
Avibactam-Natrium; AztreonamShortage2026-06-172026-12-311
Naloxonhydrochlorid-Dihydrat; Oxycodonhydrochlorid (Ph.Eur.)Shortage2026-06-182026-09-301
SildenafilShortage2026-06-202026-08-171
IbuprofenShortage2026-06-222026-10-282
EscitalopramShortage2026-06-222026-10-305
Valaciclovirhydrochlorid-HydratShortage2026-06-222026-09-301
LevonorgestrelShortage2026-06-222026-12-312
EntecavirShortage2026-06-232026-12-314
Kanamycinmonosulfat (Ph.Eur.)Shortage2026-06-232026-12-311
PioglitazonhydrochloridShortage2026-06-302026-10-311
Gentamicin sulfateShortage2026-06-302026-09-301
Cisatracurium BesilateShortage2026-06-302027-03-311
Fluorescein-Natrium (Ph.Eur.)Shortage2026-06-302026-11-101
EtoricoxibShortage2026-07-012026-11-034
Cefalexin-MonohydratShortage2026-07-012026-09-091
DigitoxinShortage2026-07-012027-01-291
PrednicarbatShortage2026-07-012026-08-161
Avalglucosidase alfaShortage2026-07-032026-08-131
Metoprololtartrat (Ph.Eur.)Shortage2026-07-042026-09-251
Sumatriptan succinateShortage2026-07-062026-10-301
TerbinafinhydrochloridShortage2026-07-062026-08-211
LanthanShortage2026-07-062027-03-151
Econazolnitrat; TriamcinolonacetonidShortage2026-07-072026-09-171
Kaliumiodid; Levothyroxin-NatriumShortage2026-07-082026-08-312
Fusidinsäure (Ph.Eur.)Shortage2026-07-082026-08-161
LiraglutideShortage2026-07-092027-03-311
PlerixaforShortage2026-07-152026-12-311
PregabalinShortage2026-07-202026-09-281
LinezolidShortage2026-07-202026-08-311
LoperamidhydrochloridShortage2026-07-202026-10-052
Olanzapinembonat-MonohydratShortage2026-07-222026-11-253
Alglucosidase alfaShortage2026-07-272026-08-101
Lidocainhydrochlorid-MonohydratShortage2026-07-282026-10-091
Dexamethasondihydrogenphosphat-Dinatrium (Ph.Eur.); GentamicinsulfatShortage2026-07-282026-10-311
GlucagonShortage2026-07-302026-11-161
Morfinhemisulfat-2,5-hydratShortage2026-07-312026-10-051
Dinatrium-pentacyanonitrosylferrat(2-)Shortage2026-08-012026-10-311
Thiopental-Natrium und Natriumcarbonat (Ph.Eur.)Shortage2026-08-072026-09-301
Calcium, CholecalciferolShortage2026-08-102027-01-311
Iobenguan ((123)I)Shortage2026-08-102026-08-281
Natriumiodid ((123)I)Shortage2026-08-102026-08-281
Fludarabinphosphat (Ph.Eur.)Shortage2026-08-202026-12-311
CefotaximeShortage2026-09-012026-11-302
Vinfluninbis[(R,R)-tartrat]Shortage2026-09-012027-05-011
Midodrine hydrochlorideShortage2026-10-272026-12-021
EsmololhydrochloridShortage2027-05-012027-12-311

Other countries

Every row links to the medicine's Europe-wide page; statuses come from the official register linked above and can change daily. Not medical advice.

Frequently asked

How many medicines are currently in shortage in Germany?

As of 7 August 2026, 225 medicines have open availability reports in BfArM (Germany), covering 496 product-level entries. 12 new reports were filed in August 2026.

Where does Germany publish its official shortage list?

BfArM (Germany) — this page aggregates it daily and links every entry back to the official record. BfArM logs company-reported Lieferengpässe per product, flags hospital-relevant cases, and usually names an alternative product — one medicine can appear once per strength.

Can a German pharmacy give me a substitute without a new prescription?

Within limits, yes. During a listed Lieferengpass, pharmacies may hand out a different pack size, strength or dosage form of the same active substance without a new prescription. A switch to a different active substance still needs your prescriber — BfArM's register usually names candidate alternatives.

Why does Germany have so many medicine shortages?

Most stated causes in the register are production problems and increased demand, but the structural driver is economic: rebate tenders concentrate each generic on very few suppliers, and much active-ingredient production sits outside Europe. When one plant fails, there is often no second source serving the German market.

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Newsrooms and health sites may embed the live Germany shortage count — free, with attribution:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/country/de/embed.html" width="100%" height="130" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Medicine shortages in Germany"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/country/de/">Medicine shortages in Germany — European Medicine Shortage Tracker</a> by MobiDoctor</p>