← European Medicine Shortage Tracker

Medicine shortages in Germany 🇩🇪 — Lieferengpass

Availability information only — Mobi Doctor doesn't sell medicines; check with a pharmacy.

MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

227 medicines currently affected according to BfArM (Germany) · updated 5 November 2026

Shortage 481

Key facts

481 product-level reports are open, 14 new reports were filed in November 2026. Where the register states a cause, the leading ones are manufacturing problems (244), unexpectedly high demand (121) out of 365 reports with a stated cause. The longest-running open case is Hydrochlorothiazid; Valsartan, reported on 2018-07-01 — about 100 months ago.

How to read this register: BfArM logs company-reported Lieferengpässe per product, flags hospital-relevant cases, and usually names an alternative product — one medicine can appear once per strength.

How medicine shortages are managed in Germany

Pharmaceutical companies report supply interruptions of prescription medicines to BfArM, which publishes them in the register this page tracks.

A standing advisory board (Beirat) at BfArM reviews the list and classifies which shortages are supply-critical (versorgungskritisch); those get active management — data requests, stock monitoring, and coordination with hospitals and wholesalers.

Since the 2023 ALBVVG supply law, pharmacies may deviate from the prescribed pack size, strength or dosage form of the same active substance during a listed shortage without sending the patient back to the prescriber — a flexibility made permanent after the pandemic.

If the health ministry formally declares a Versorgungsmangel (supply emergency), temporary imports of foreign-labelled packs become permissible for that medicine.

Structurally, Germany's rebate-contract system concentrates generic supply on few winners per substance, which is why a single manufacturing problem can empty the market — a dynamic the ALBVVG tries to soften for antibiotics and children's medicines.

What to do if your medicine is affected in Germany

If your medicine appears here, ask your Apotheke first: German rules give pharmacies extra substitution flexibility during declared shortages, and BfArM's register usually names an alternative product (see the Alternatives column). For hospital-relevant medicines, supplies are actively managed. Your prescriber can switch you to a listed equivalent where one exists. Never stop a treatment on your own — confirm any switch with your pharmacist or prescriber.

Searched locally as: Lieferengpass, Lieferengpässe, Medikament nicht lieferbar.

Newest reports

MedicineStatusReportedExpected end
EsmololShortage2027-05-012027-12-31
PentostatinShortage2027-03-012028-09-30
CiprofloxacinShortage2026-12-042027-01-15
Calciumchlorid-Dihydrat; Glucose-Monohydrat (Ph.Eur.); Kaliumchlorid; Magnesiumchlorid-Hexahydrat; Natriumacetat-Trihydrat; NatriumchloridShortage2026-11-302027-09-30
IsofluranShortage2026-11-162027-03-12
Clindamycin phosphateShortage2026-11-052027-01-15
ClonidinhydrochloridShortage2026-11-052026-12-21
Sulfaméthoxazole, triméthoprimeShortage2026-11-052027-01-11
Clindamycin-2-dihydrogenphosphat; TretinoinShortage2026-11-052026-11-21
Metoprololtartrat (Ph.Eur.)Shortage2026-11-032027-02-16

All affected medicines

MedicineStatusSince Expected endReports
Hydrochlorothiazid; ValsartanShortage2018-07-012026-12-313
CefiximeShortage2018-10-012026-12-311
Fibrinogen vom MenschenShortage2019-05-012027-01-311
Natrium(hydrocortison-21-succinat)Shortage2019-07-012026-12-311
Flucloxacillin-Natrium 1 H<2>OShortage2020-08-012027-02-151
Eisen(III)-hexacyanoferrat(II)Shortage2021-02-242026-12-311
BCG-Bakterien, Stamm TICE, lebend, attenuiertShortage2021-03-012027-12-311
VerteporfinShortage2021-07-012026-12-311
PenicillaminShortage2022-03-202027-03-311
Bendamustine hydrochlorideShortage2022-05-012026-12-311
Calcium folinate hydrateShortage2022-05-062028-09-153
SomatostatinacetatShortage2022-12-092026-12-311
Rosuvastatin-HemicalciumShortage2023-03-062027-07-317
AlprostadilShortage2023-03-162028-01-153
MelperonhydrochloridShortage2023-03-242026-12-312
Desogestrel, etinylestradiolShortage2023-03-312026-12-311
VindesineShortage2023-10-232027-03-301
GemcitabinhydrochloridShortage2023-12-042027-01-311
AdenosineShortage2024-03-012027-12-312
IsosorbidmononitratShortage2024-04-082027-01-042
Amoxicillin-TrihydratShortage2024-05-012026-12-011
FluconazoleShortage2024-06-012026-12-311
Terazosinhydrochlorid-DihydratShortage2024-07-012027-03-316
Quetiapinfumarat (Ph.Eur.)Shortage2024-07-232027-04-1542
AprepitantShortage2024-08-012027-04-306
Doxorubicin hydrochlorideShortage2024-08-162027-01-193
FluorometholonShortage2024-08-222026-12-311
RisperidoneShortage2024-09-052027-06-309
Calciumchlorid-Dihydrat; Histidin; Histidinhydrochlorid-Monohydrat; Kalium-hydrogen-2-oxopentandioat; Kaliumchlorid; Magnesiumchlorid-Hexahydrat; Mannitol (Ph.Eur.); Natriumchlorid; TryptophanShortage2024-09-182026-12-311
GalantaminaShortage2024-10-022027-12-3115
Levothyroxin-Natrium (Ph.Eur.)Shortage2024-11-012026-12-312
Mannitol (Ph.Eur.)Shortage2024-11-012026-11-301
DarifenacinhydrobromidShortage2024-11-042030-01-012
Fosfomycin-Natrium (Ph.Eur.)Shortage2024-11-052027-03-312
LevomepromazinhydrochloridShortage2024-11-152028-05-152
PrednisoloneShortage2024-11-212027-03-014
Methyldopa (Ph.Eur.)Shortage2024-12-022026-12-182
Liothyronin-NatriumShortage2024-12-022027-02-011
TeicoplaninShortage2024-12-182027-03-312
LevetiracetamShortage2025-01-012026-12-3110
ProcainhydrochloridShortage2025-01-102027-08-312
VancomycinhydrochloridShortage2025-01-152026-11-301
DistigminbromidShortage2025-01-302026-12-311
KandesartancilexetilShortage2025-02-112028-10-055
Tacrolimus-MonohydratShortage2025-02-152026-12-315
Pramipexoldihydrochlorid-MonohydratShortage2025-03-032027-01-283
Calciumacetat; Schweres, basisches MagnesiumcarbonatShortage2025-03-242027-03-311
Atorvastatin-Calcium-Trihydrat (Ph.Eur.)Shortage2025-03-282026-12-315
Natrium(methylprednisolon-21-succinat)Shortage2025-03-312027-06-305
Calciumchlorid-Dihydrat; Magnesiumchlorid-Hexahydrat; Natriumchlorid; NatriumhydrogencarbonatShortage2025-04-012027-04-011
SertralineShortage2025-04-142027-01-153
NifedipineShortage2025-04-152026-12-312
RibavirineShortage2025-05-022027-06-302
OxcarbazepinShortage2025-05-092026-11-301
EsomeprazoleShortage2025-05-222026-12-314
Insulin aspartShortage2025-05-312026-12-311
NitrendipineShortage2025-06-022026-12-311
BortezomibmannitolShortage2025-06-022026-11-201
Epoetin betaShortage2025-06-092027-06-304
(2-Aminoethyl)dihydrogenphosphat-Calciumsalz (1:1)Shortage2025-06-112026-12-181
TrospiumchloridShortage2025-06-112027-09-301
CiprofloxacinShortage2025-07-012027-01-152
Doxepinhydrochlorid (Ph.Eur.)Shortage2025-07-072026-12-313
PromethazinhydrochloridShortage2025-07-152028-07-151
Minocyclinhydrochlorid-Dihydrat (Ph.Eur.)Shortage2025-07-152027-03-311
Amlodipinbesilat; Perindopril-tert-butylaminShortage2025-07-162026-11-151
DinoprostonShortage2025-07-212027-02-283
BudesonideShortage2025-08-012026-12-311
SalbutamolShortage2025-08-012027-02-012
Beclometasondipropionat (Ph.Eur.)Shortage2025-08-012026-12-312
Von Willebrand-FaktorShortage2025-08-012026-11-301
CalcitriolShortage2025-08-262026-12-312
Ezetimibe, SimvastatinShortage2025-09-012026-11-304
BesilesomabShortage2025-09-172028-06-261
TranexamsäureShortage2025-09-292027-03-301
CytarabineShortage2025-10-072027-12-314
IsotretinoinShortage2025-10-112026-12-316
VinorelbinaShortage2025-10-152026-12-311
FlutamidShortage2025-10-222026-12-011
AdalimumabShortage2025-11-012027-01-202
Dexamethasonacetat (Ph.Eur.); Lidocainhydrochlorid-MonohydratShortage2025-11-012027-11-012
MesalazineShortage2025-11-052026-11-161
Lanreotidacetat (1:x) ((mit Angaben zum Essigsäure-Gehalt))Shortage2025-11-092027-02-021
Tolterodine tartrateShortage2025-11-142028-01-031
MitomycineShortage2025-11-182027-02-011
TriamcinolonacetonidShortage2025-11-242027-01-057
BenperidolShortage2025-11-242028-03-151
IvermektinShortage2025-11-282026-12-141
Cefaclor-MonohydratShortage2025-12-012026-12-314
MethantheliniumbromidShortage2025-12-012026-12-311
IsoniazidShortage2025-12-082027-02-222
Paliperidon palmitatShortage2025-12-092027-03-075
DinatriumpamidronatShortage2025-12-112026-12-311
Dexamethasondihydrogenphosphat-Dinatrium (Ph.Eur.)Shortage2025-12-152028-03-315
Nilotinibhydrochlorid-DihydratShortage2025-12-192026-12-151
TobramycineShortage2026-01-012026-11-301
KarmustinShortage2026-01-052026-12-311
ErythromycinlactobionatShortage2026-01-092026-12-311
CyclophosphamideShortage2026-01-212026-12-313
IfosfamideShortage2026-01-212027-12-315
AbirateronaShortage2026-01-212027-01-151
Duloxetine hydrochlorideShortage2026-01-232026-12-312
Pantoprazol-Natrium-SesquihydratShortage2026-02-012026-11-305
CrisantaspaseShortage2026-02-042026-12-311
UrapidilShortage2026-02-092027-06-074
RitonavirShortage2026-02-122027-09-301
AciclovirShortage2026-02-162027-03-292
Bisoprololfumarat (Ph.Eur.); HydrochlorothiazidShortage2026-02-192026-12-312
Acetylcystein; Alanin; Arginin; Glycin; Histidin; Isoleucin; L-Äpfelsäure; Leucin; Lysinacetat; Methionin; N-Acetyltyrosin (Ph.Eur.); Phenylalanin; Prolin; Serin; Taurin; Threonin; Tryptophan; ValinShortage2026-02-192026-12-311
Alanin; Arginin; Glycin; Histidin; Isoleucin; Leucin; Lysinacetat; Methionin; Phenylalanin; Prolin; Serin; Taurin; Threonin; Tryptophan; Tyrosin; ValinShortage2026-02-192026-12-311
PropranololhydrochloridShortage2026-02-252026-11-271
Eletriptan hydrobromidShortage2026-03-012026-12-314
GolimumabShortage2026-03-012027-05-031
ClomifencitratShortage2026-03-092027-02-021
ValsartanShortage2026-03-192026-12-313
Amitriptyline hydrochlorideShortage2026-03-262026-11-203
OlanzapineShortage2026-04-012026-12-317
PazopanibhydrochloridShortage2026-04-012026-12-091
CefuroximaxetilShortage2026-04-012026-11-302
Mittelkettige Triglyceride; Omega-3-Säuren-reiches Fischöl ((mit Angaben zur Zusammensetzung)); Raffiniertes Olivenöl; Raffiniertes Sojaöl (Ph.Eur.)Shortage2026-04-022026-12-311
ErythromycinestolatShortage2026-04-102027-06-301
Bisoprololfumarat (Ph.Eur.)Shortage2026-04-172027-12-313
Dabigatran etexilatoShortage2026-04-212026-12-153
(RS)-2,3-Bis(sulfanyl)propan-1-sulfonsäure-Natriumsalz-MonohydratShortage2026-04-222027-02-282
Acetylcystein; Alanin; Arginin; Essigsäure 99%; Glycin; Histidin; Isoleucin; Leucin; Lysinacetat; Methionin; Phenylalanin; Prolin; Serin; Threonin; Tryptophan; ValinShortage2026-04-222026-12-311
PhényléphrineShortage2026-04-272026-11-302
PropofolShortage2026-05-012026-12-312
Metoprololsuccinat (Ph.Eur.)Shortage2026-05-072026-11-301
DiltiazemhydrochloridShortage2026-05-112027-03-314
KarboplatinShortage2026-05-152026-12-311
AcetylcholinchloridShortage2026-05-152027-01-151
IdarubicinhydrochloridShortage2026-05-192027-02-192
Fluorescein-Natrium (Ph.Eur.); OxybuprocainhydrochloridShortage2026-05-192026-12-071
DorzolamidhydrochloridShortage2026-05-262026-12-011
Metoprololtartrat (Ph.Eur.)Shortage2026-05-302027-03-093
FingolimodShortage2026-06-012027-01-302
CabergolinShortage2026-06-012026-12-152
DexamethasonShortage2026-06-012027-01-291
Ampicillin-Natrium; Sulbactam-NatriumShortage2026-06-012028-03-311
MelphalanhydrochloridShortage2026-06-052026-12-311
OxytocinShortage2026-06-082026-11-071
RizatriptanbenzoatShortage2026-06-102026-11-271
RivaroxabanShortage2026-06-152028-12-312
CarbamazépineShortage2026-06-162026-12-151
Avibactam-Natrium; AztreonamShortage2026-06-172026-12-311
EscitalopramShortage2026-06-222027-01-305
LevonorgestrelShortage2026-06-222026-12-312
Kanamycinmonosulfat (Ph.Eur.)Shortage2026-06-232026-12-311
Cisatracurium BesilateShortage2026-06-302027-03-312
Gentamicin sulfateShortage2026-06-302026-12-311
Fluorescein-Natrium (Ph.Eur.)Shortage2026-06-302026-11-101
EtoricoxibShortage2026-07-012026-12-165
DigitoxinShortage2026-07-012027-01-291
Avalglucosidase alfaShortage2026-07-032026-12-311
Sumatriptan succinateShortage2026-07-062026-12-011
LanthanShortage2026-07-062027-03-153
LiraglutideShortage2026-07-092027-03-311
PlerixaforShortage2026-07-152026-12-311
EntecavirShortage2026-07-282027-08-318
Dexamethasondihydrogenphosphat-Dinatrium (Ph.Eur.); GentamicinsulfatShortage2026-07-282026-11-301
MethotrexateShortage2026-07-292026-12-312
OxaloplatinShortage2026-07-312026-12-311
Latanoprost, timololmaleatShortage2026-08-012027-01-011
Dinatrium-pentacyanonitrosylferrat(2-)Shortage2026-08-012026-12-311
RopivacainhydrochloridShortage2026-08-032026-11-274
Triamteren; XipamidShortage2026-08-052027-04-301
Trandolapril; VerapamilhydrochloridShortage2026-08-062026-11-161
KolekalciferolShortage2026-08-102027-01-311
PrednicarbatShortage2026-08-102026-11-222
NatriumhydrogencarbonatShortage2026-08-112027-06-152
MepivacainhydrochloridShortage2026-08-192026-11-231
Fludarabinphosphat (Ph.Eur.)Shortage2026-08-202026-12-311
Pankreas-Pulver vom SchweinShortage2026-08-252026-12-012
MivacuriumchloridShortage2026-08-262026-11-301
Natriumcromoglicat (Ph.Eur.); ReproterolhydrochloridShortage2026-08-272027-03-012
Indapamid; PerindopriltosilatShortage2026-08-282026-12-151
Lidocain; PrilocainShortage2026-08-312026-12-311
Cefotaxim-NatriumShortage2026-09-012026-11-302
AmiodaronhydrochloridShortage2026-09-012026-11-231
Vinfluninbis[(R,R)-tartrat]Shortage2026-09-012027-05-011
TrofosfamidShortage2026-09-032026-11-201
TravoprostShortage2026-09-072027-01-151
AmisulpridShortage2026-09-072026-11-201
IohexolShortage2026-09-112026-11-111
Ezetimib; Rosuvastatin-Calcium (Ph.Eur.)Shortage2026-09-112026-11-062
Econazolnitrat; TriamcinolonacetonidShortage2026-09-112026-12-181
Calciumcarbonat; ColecalciferolShortage2026-09-142027-01-311
ValganciclovirhydrochloridShortage2026-09-172026-12-011
MédroxyprogestéroneShortage2026-09-172026-12-142
NévirapineShortage2026-09-172027-04-151
Olanzapinembonat-MonohydratShortage2026-09-192026-12-021
GlucagonShortage2026-09-212026-11-271
Insulin glarginShortage2026-09-212026-11-181
NitrofurantoinShortage2026-09-252026-11-051
Triamcinolonacetonid; ZinkoxidShortage2026-09-252026-12-311
Phenoxymethylpenicillin calciumShortage2026-09-302026-11-301
Ceftobiprolmedocaril-NatriumShortage2026-09-302027-04-151
MethioninShortage2026-10-012026-12-081
MilrinonShortage2026-10-022026-11-061
EncorafenibShortage2026-10-052026-11-152
Epoetin zetaShortage2026-10-062026-11-301
NatriumthiosulfatShortage2026-10-082026-11-291
Konzentrat proteolytischer Enzyme angereichert aus BromelainShortage2026-10-082026-11-301
TimololoShortage2026-10-132026-11-061
TrifarotenShortage2026-10-132026-11-121
Foscarnet-Natrium-HexahydratShortage2026-10-132026-11-131
RifampicinShortage2026-10-192026-12-071
SpironolactoneShortage2026-10-202026-12-311
Samarium-((153)Sm)-Lexidronam-PentanatriumShortage2026-10-202026-12-311
AjmalineShortage2026-10-222026-11-301
Ipratropiumbromid (monohydrat)Shortage2026-10-222027-04-011
Indapamid; Perindopril-ArgininShortage2026-10-232026-12-201
Sulbactam-NatriumShortage2026-10-232026-12-311
Olipudase alfaShortage2026-10-262026-12-311
Poly(styrol-co-divinylbenzol)sulfonsäure-(x:y)-NatriumsalzShortage2026-10-262026-11-231
GranisetronhydrochloridShortage2026-10-302026-12-141
DacarbazincitratShortage2026-10-312026-12-151
Calciumchlorid-Dihydrat; Glucose-Monohydrat (Ph.Eur.); Kaliumchlorid; Magnesiumchlorid-Hexahydrat; Natriumacetat-Trihydrat; NatriumchloridShortage2026-11-012027-09-302
SulfadiazinShortage2026-11-022027-03-311
PalipéridoneShortage2026-11-032027-08-071
Clindamycin phosphateShortage2026-11-052027-01-151
ClonidinhydrochloridShortage2026-11-052026-12-211
Sulfaméthoxazole, triméthoprimeShortage2026-11-052027-01-111
Clindamycin-2-dihydrogenphosphat; TretinoinShortage2026-11-052026-11-211
IsofluranShortage2026-11-162027-03-121
PentostatinShortage2027-03-012028-09-301
EsmololShortage2027-05-012027-12-311

Shortages by country

Every row links to the medicine's Europe-wide page; statuses come from the official register linked above and can change daily. Not medical advice.

Frequently asked

How many medicines are currently in shortage in Germany?

As of 5 November 2026, 227 medicines have open availability reports in BfArM (Germany), covering 481 product-level entries. 14 new reports were filed in November 2026.

Where does Germany publish its official shortage list?

BfArM (Germany) — this page aggregates it daily and links every entry back to the official record. BfArM logs company-reported Lieferengpässe per product, flags hospital-relevant cases, and usually names an alternative product — one medicine can appear once per strength.

Can a German pharmacy give me a substitute without a new prescription?

Within limits, yes. During a listed Lieferengpass, pharmacies may hand out a different pack size, strength or dosage form of the same active substance without a new prescription. A switch to a different active substance still needs your prescriber — BfArM's register usually names candidate alternatives.

Why does Germany have so many medicine shortages?

Most stated causes in the register are production problems and increased demand, but the structural driver is economic: rebate tenders concentrate each generic on very few suppliers, and much active-ingredient production sits outside Europe. When one plant fails, there is often no second source serving the German market.

Embed this counter

Newsrooms and health sites may embed the live Germany shortage count — free, with attribution:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/country/de/embed.html" width="100%" height="130" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Medicine shortages in Germany"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/country/de/">Medicine shortages in Germany — European Medicine Shortage Tracker</a> by MobiDoctor</p>