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Dinoproston currently has availability issues reported in 5 European registers: Austria, Germany, Greece, Italy, Sweden.
Shortage ATC G02AD02 · also listed as: DINOPROSTON · dinoprostone · data refreshed 28 October 2026
As of 28 October 2026, 5 of the 10 tracked registers list current availability issues for Dinoproston, covering 11 affected product presentations. The longest-running open report was filed in Germany on 2025-07-21 and has now been open for about 15 months. Where agencies state a cause, manufacturing problems lead with 5 of the 7 stated-cause reports, followed by unexpectedly high demand with 1. The furthest expected-resolution date currently on file is 2027-02-28; the earliest is 2026-10-31. Notably, 5 reports have already passed the expected-resolution date without closing — prognoses for this medicine should be read as estimates, not commitments. The issue spread across registers over time rather than at once: Germany reported first (2025-07-21), with Sweden following roughly 6 months later — a pattern typical of supply problems cascading between national markets. Registers in Germany, Greece, Italy, Sweden indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Dinoproston is coded G02AD02 — a medicine acting on the genito-urinary system and sex hormones — so clinically related products appear under “Related medicines” below.
| Where | Status & products | Since | Expected end | Reason / alternatives | Source |
|---|---|---|---|---|---|
| 🇦🇹 Austria | Shortage Prostin E2 3 mg - Vaginaltabletten (PZN 1106746) | 2025-07-30 | 2026-10-15 | Verzögerung bei der Herstellung | register ↗ |
| 🇩🇪 Germany | Shortage Minprostin E2 Vaginalgel 1mg + 3 more productsMinprostin E2 Vaginalgel 2mg Minprostin E2 Vaginaltabletten Prepidil Gel | 2025-07-21 | 2027-02-28 | Probleme beim Wirkstoffhersteller Alternatives: N/A | register ↗ |
| 🇫🇷 France | Resolved Prostine E2 1 mg/3 g, gel vaginal | 2026-08-19 | 2026-08-19 | Gynécologie | register ↗ |
| 🇬🇷 Greece | Limited availability Dinoproston + 1 more productsPROSTIN E2 VAG.TAB 3MG/TAB ΒΤX4 | 2025-12-15 | 2026-08-31 | Ν Ι.Φ.Ε.Τ. ΕΡΕΥΝΑ ΑΓΟΡΑΣ Alternatives: ΑΝΑΜΕΝΕΤΑΙ | register ↗ |
| 🇮🇹 Italy | Shortage PREPIDIL + 1 more productsPREPIDIL | 2025-10-06 | 2026-12-30 | Problemi produttivi Alternatives: AIFA: import of a foreign equivalent can be authorised. | register ↗ |
| 🇸🇪 Sweden | Shortage Minprostin 1 mg Vaginalgel + 1 more productsMinprostin 2 mg Vaginalgel | 2026-01-19 | 2026-10-23 | — Alternatives: Alternative(s) available — see the national register. | register ↗ |
Every individual register entry for Dinoproston in the tracked sources, newest first — including resolved and discontinued reports.
| Reg. | Product | Status | Reported | Expected end | Stated reason |
|---|---|---|---|---|---|
| 🇫🇷 FR | Prostine E2 1 mg/3 g, gel vaginal | Resolved | 2026-08-19 | 2026-08-19 | Gynécologie |
| 🇬🇷 GR | Dinoproston | Limited availability | 2026-07-03 | 2026-08-20 | Ν Ι.Φ.Ε.Τ. ΕΡΕΥΝΑ ΑΓΟΡΑΣ |
| 🇸🇪 SE | Minprostin 2 mg Vaginalgel | Shortage | 2026-03-30 | 2026-10-23 | |
| 🇩🇪 DE | Prepidil Gel | Shortage | 2026-01-23 | 2027-02-28 | Erhöhte Nachfrage |
| 🇸🇪 SE | Minprostin 1 mg Vaginalgel | Shortage | 2026-01-19 | 2026-10-09 | |
| 🇮🇹 IT | PREPIDIL | Shortage | 2025-12-22 | 2026-11-30 | Problemi produttivi |
| 🇬🇷 GR | PROSTIN E2 VAG.TAB 3MG/TAB ΒΤX4 | Limited availability | 2025-12-15 | 2026-08-31 | PFIZER ΕΛΛΑΣ Α.Ε. Καθυστέρηση παράδοσης Εναλλακτικά μέσω έκτ |
| 🇩🇪 DE | Minprostin E2 Vaginalgel 1mg | Shortage | 2025-12-01 | 2026-10-31 | Probleme beim Wirkstoffhersteller |
| 🇩🇪 DE | Minprostin E2 Vaginalgel 2mg | Shortage | 2025-12-01 | 2026-11-30 | Probleme beim Wirkstoffhersteller |
| 🇮🇹 IT | PREPIDIL | Shortage | 2025-10-06 | 2026-12-30 | Problemi produttivi |
| 🇦🇹 AT | Prostin E2 3 mg - Vaginaltabletten (PZN 1106746) | Shortage | 2025-07-30 | 2026-10-15 | Verzögerung bei der Herstellung |
| 🇩🇪 DE | Minprostin E2 Vaginaltabletten | Shortage | 2025-07-21 | 2027-02-28 | Sonstige |
Yes. As of 28 October 2026, availability issues are reported in: Austria, Germany, Greece, Italy, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.
Agency prognoses on file range from 2026-10-31 to 2027-02-28. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.
10 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.
Directly from the official medicines-agency registers that list Dinoproston: BASG (Austria), BfArM (Germany), ANSM (France), EOF limited-availability list (Greece), AIFA (Italy), Läkemedelsverket (Sweden). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.
Pharmacies, patient sites and newsrooms are welcome to embed the live status of Dinoproston — free, with attribution. Copy this snippet:
<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/dinoproston/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Dinoproston availability in Europe"></iframe> <p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/dinoproston/">Dinoproston shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>