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Alprostadil shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Alprostadil currently has availability issues reported in 3 European registers: Germany, France, Sweden.

Shortage  ATC C01EA01 · also listed as: Alprostadil · data refreshed 12 September 2026

Key facts

As of 12 September 2026, 3 of the 9 tracked registers list current availability issues for Alprostadil, covering 6 affected product presentations. The longest-running open report was filed in Germany on 2023-03-16 and has now been open for about 42 months. Where agencies state a cause, unexpectedly high demand lead with 1 of the 1 stated-cause reports. The furthest expected-resolution date currently on file is 2028-01-15; the earliest is 2026-12-31. Notably, 2 reports have already passed the expected-resolution date without closing — prognoses for this medicine should be read as estimates, not commitments. Registers in Germany, Sweden indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Alprostadil is coded C01EA01 — a medicine acting on the cardiovascular system — so clinically related products appear under “Related medicines” below.

WhereStatus & productsSinceExpected end Reason / alternativesSource
🇩🇪 GermanyShortage
Muse 1000 mikrogramm
+ 2 more products
Muse 500 mikrogramm
Prostavasin 20 µg
2023-03-162028-01-15Sonstige
Alternatives: N/A
register ↗
🇫🇷 FranceShortage
Alprostadil Intsel Chimos 0,5 mg/ml, solution injectable
Cardiologieregister ↗
🇸🇪 SwedenShortage
Caverject Dual 10 mikrogram Pulver och vätska till injektionsvätska, lösning
+ 1 more products
Caverject Dual 20 mikrogram Pulver och vätska till injektionsvätska, lösning
2023-07-112026-08-07
Alternatives: Alternative(s) available — see the national register.
register ↗

New register reports per month

2025-06: 12025-07: 02025-08: 02025-09: 02025-10: 02025-11: 02025-12: 02026-01: 02026-02: 12025-062026-02

Full report history (6 register entries)

Every individual register entry for Alprostadil in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇩🇪 DEProstavasin 20 µgShortage2026-02-042026-12-31Erhöhte Nachfrage
🇸🇪 SECaverject Dual 10 mikrogram Pulver och vätska till injektionsvätska, lShortage2025-06-232026-07-31
🇸🇪 SECaverject Dual 20 mikrogram Pulver och vätska till injektionsvätska, lShortage2023-07-112026-08-07
🇩🇪 DEMuse 1000 mikrogrammShortage2023-03-162028-01-15Sonstige
🇩🇪 DEMuse 500 mikrogrammShortage2023-03-162028-01-15Sonstige
🇫🇷 FRAlprostadil Intsel Chimos 0,5 mg/ml, solution injectableShortageCardiologie

Frequently asked

Is Alprostadil currently in shortage in Europe?

Yes. As of 12 September 2026, availability issues are reported in: Germany, France, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.

When is the Alprostadil shortage expected to end?

Agency prognoses on file range from 2026-12-31 to 2028-01-15. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.

Are there alternatives to Alprostadil?

5 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Alprostadil availability data come from?

Directly from the official medicines-agency registers that list Alprostadil: BfArM (Germany), ANSM (France), Läkemedelsverket (Sweden). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Related medicines (same ATC class)

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the live status of Alprostadil — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/alprostadil/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Alprostadil availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/alprostadil/">Alprostadil shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Alprostadil: availability status across 3 European registers — European Medicine Shortage Tracker (MobiDoctor), 12 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.