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Doxorubicin hydrochloride shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Doxorubicin hydrochloride currently has availability issues reported in 4 European registers: Germany, Spain, Ireland, Sweden.

Shortage  ATC L01DB01 · also listed as: Doxorubicinhydrochlorid · DOXORUBICINA · DOXORUBICIN HYDROCHLORIDE · doxorubicinhydroklorid · data refreshed 12 September 2026

Key facts

As of 12 September 2026, 4 of the 9 tracked registers list current availability issues for Doxorubicin hydrochloride, covering 8 affected product presentations. The longest-running open report was filed in Germany on 2024-08-16 and has now been open for about 25 months. Where agencies state a cause, manufacturing problems lead with 4 of the 4 stated-cause reports. The furthest expected-resolution date currently on file is 2027-01-19; the earliest is 2026-09-30. Notably, 1 report has already passed the expected-resolution date without closing — prognoses for this medicine should be read as estimates, not commitments. The issue spread across registers over time rather than at once: Germany reported first (2024-08-16), with Spain following roughly 16 months later — a pattern typical of supply problems cascading between national markets. Registers in Germany, Spain, Ireland, Sweden indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Doxorubicin hydrochloride is coded L01DB01 — a medicine acting on antineoplastic and immunomodulating agents — so clinically related products appear under “Related medicines” below.

WhereStatus & productsSinceExpected end Reason / alternativesSource
🇩🇪 GermanyShortage
DOXO-cell 150 mg Injektionslösung
+ 2 more products
DOXO-cell 50 mg Injektionslösung
Doxorubicinhydrochlorid Bendalis 2 mg/ml
2024-08-162027-01-19Probleme in der Herstellung
Alternatives: N/A
register ↗
🇪🇸 SpainShortage
DOXORUBICINA ACCORD 2 MG/ML CONCENTRADO PARA SOLUCION PARA PERFUSION EFG, 1 via de 50 ml
2025-12-172026-10-29Existen otros medicamentos con el mismo principio activo y misma vía.
Alternatives: Existe/n otro/s medicamento/s con el mismo principio activo y para la misma vía de administración.
register ↗
🇮🇪 IrelandShortage
Doxorubicin Teva 2 mg / ml Concentrate for Solution for Infusion
2024-11-05Manufacturing delay
Alternatives: Alternative(s) available — see the national register.
register ↗
🇸🇪 SwedenShortage
Doxorubicin Teva 2 mg/ml Injektionsvätska, lösning
+ 2 more products
Zolsketil pegylated liposomal 2 mg/ml Koncentrat till infusionsvätska, dispersio
Zolsketil pegylated liposomal 2 mg/ml Koncentrat till infusionsvätska, dispersio
2025-01-012026-12-31
Alternatives: Alternative(s) available — see the national register.
register ↗

New register reports per month

2024-08: 12024-09: 12024-10: 02024-11: 22024-12: 02025-01: 12025-02: 02025-03: 02025-04: 02025-05: 02025-06: 02025-07: 02025-08: 02025-09: 02025-10: 02025-11: 02025-12: 12026-01: 02026-02: 22024-082026-02

Full report history (8 register entries)

Every individual register entry for Doxorubicin hydrochloride in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇸🇪 SEZolsketil pegylated liposomal 2 mg/ml Koncentrat till infusionsvätska,Shortage2026-02-062026-09-30
🇸🇪 SEZolsketil pegylated liposomal 2 mg/ml Koncentrat till infusionsvätska,Shortage2026-02-062026-08-31
🇪🇸 ESDOXORUBICINA ACCORD 2 MG/ML CONCENTRADO PARA SOLUCION PARA PERFUSION EShortage2025-12-172026-10-29Existen otros medicamentos con el mismo principio activo y m
🇸🇪 SEDoxorubicin Teva 2 mg/ml Injektionsvätska, lösningShortage2025-01-012026-12-31
🇩🇪 DEDoxorubicinhydrochlorid Bendalis 2 mg/mlShortage2024-11-152026-12-31Probleme in der Herstellung
🇮🇪 IEDoxorubicin Teva 2 mg / ml Concentrate for Solution for InfusionShortage2024-11-05Manufacturing delay
🇩🇪 DEDOXO-cell 150 mg InjektionslösungShortage2024-09-162027-01-19Probleme in der Herstellung
🇩🇪 DEDOXO-cell 50 mg InjektionslösungShortage2024-08-162027-01-19Probleme in der Herstellung

Frequently asked

Is Doxorubicin hydrochloride currently in shortage in Europe?

Yes. As of 12 September 2026, availability issues are reported in: Germany, Spain, Ireland, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.

When is the Doxorubicin hydrochloride shortage expected to end?

Agency prognoses on file range from 2026-09-30 to 2027-01-19. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.

Are there alternatives to Doxorubicin hydrochloride?

8 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Doxorubicin hydrochloride availability data come from?

Directly from the official medicines-agency registers that list Doxorubicin hydrochloride: BfArM (Germany), AEMPS CIMA (Spain), HPRA (Ireland), Läkemedelsverket (Sweden). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Related medicines (same ATC class)

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<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/doxorubicin-hydrochloride/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Doxorubicin hydrochloride availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/doxorubicin-hydrochloride/">Doxorubicin hydrochloride shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Doxorubicin hydrochloride: availability status across 4 European registers — European Medicine Shortage Tracker (MobiDoctor), 12 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.