← European Medicine Shortage Tracker · all medicines

Dinoproston shortage — availability across Europe

Availability information only — Mobi Doctor doesn't sell medicines; check with a pharmacy.

MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Dinoproston currently has availability issues reported in 5 European registers: Austria, Germany, Greece, Italy, Sweden.

Shortage  ATC G02AD02 · also listed as: DINOPROSTON · dinoprostone · registers read 14 November 2026 (Greece: list dated 31 October 2026, posted 9 November 2026)

Key facts

As of 14 November 2026 (Greece: list dated 31 October 2026, posted 9 November 2026), 5 of the 10 tracked registers list current availability issues for Dinoproston, covering 9 affected product presentations. The longest-running open report was filed in Germany on 2025-07-21; it had been open for about 16 months on the day the register was read. Where a register states a cause, the most common is manufacturing problems: 4 of the 7 reports that state one, followed by active-ingredient (API) supply issues with 1. The furthest expected-resolution date on file is 2027-02-28; the earliest is 2026-11-30. On the day the register was read, 1 report had passed its expected-resolution date without closing — prognoses for this medicine should be read as estimates, not commitments. The registers did not report it at the same time: Germany reported first (2025-07-21) and Sweden about 8 months later. The registers in Germany, Greece, Italy and Sweden note alternatives, equivalents or another supply route — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Dinoproston is coded G02AD02 (group: genito-urinary system and sex hormones).

WhereStatus & productsStartExpected end Reason / alternativesSource
🇦🇹 AustriaShortage
Prostin E2 3 mg - Vaginaltabletten (PZN 1106746)
2025-07-302026-10-15Verzögerung bei der Herstellungregister ↗
🇩🇪 GermanyShortage
Minprostin E2 Vaginalgel 2mg
+ 2 more products
Minprostin E2 Vaginaltabletten
Prepidil Gel
2025-07-212027-02-28Probleme beim Wirkstoffhersteller
Alternatives: Minprostin E2 Vaginalgel 1mg - Einreichungsnummer: 2119724
register ↗
🇫🇷 FranceResolved
Prostine E2 1 mg/3 g, gel vaginal
2026-08-312026-08-19Therapeutic area: Gynécologieregister ↗
🇬🇷 GreeceLimited availability
PROSTIN E2 VAG.TAB 3MG/TAB ΒΤX4
+ 1 more product
PROSTIN E2_VAG.TAB_3MG/TAB_ΒΤ x 8
2025-12-152027-02-26Delivery delay
Alternatives: EOF: available through emergency import.
register ↗
🇮🇹 ItalyShortage
PREPIDIL — 1 MG/3 G GEL VAGINALE, 1 SIRINGA PRERIEMPITA DA 3 G
+ 1 more product
PREPIDIL — 2 MG/3 G GEL VAGINALE, 1 SIRINGA PRERIEMPITA 3 G
2025-10-062026-12-30Problemi produttivi
Alternatives: AIFA: import of a foreign equivalent can be authorised.
register ↗
🇸🇪 SwedenShortage
Minprostin 2 mg Vaginalgel — Endosspruta 2,5 ml
1 other report in this register (announced or ended): see the report history below.
2026-03-302026-12-25—
Alternatives: Läkemedelsverket lists: another medicine in the same ATC group.
register ↗

New shortage reports per month

2025-07: 22025-08: 02025-09: 02025-10: 12025-11: 02025-12: 32026-01: 22026-02: 02026-03: 12026-04: 02026-05: 02026-06: 02026-07: 02026-08: 12026-09: 02026-10: 02026-11: 12025-072026-11

Full report history (11 register entries)

Every individual register entry for Dinoproston in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusStartExpected endStated reason or register note
🇬🇷 GRPROSTIN E2_VAG.TAB_3MG/TAB_ΒΤ x 8Limited availability2026-11-032027-01-20On EOF's list of emergency-coverage products (IFET): production problem
🇫🇷 FRProstine E2 1 mg/3 g, gel vaginalResolved2026-08-312026-08-19Therapeutic area: Gynécologie
🇸🇪 SEMinprostin 2 mg Vaginalgel — Endosspruta 2,5 mlShortage2026-03-302026-12-25
🇩🇪 DEPrepidil GelShortage2026-01-232027-02-28Erhöhte Nachfrage
🇸🇪 SEMinprostin 1 mg Vaginalgel — Endosspruta 2,5 mlResolved2026-01-192026-11-06
🇮🇹 ITPREPIDIL — 1 MG/3 G GEL VAGINALE, 1 SIRINGA PRERIEMPITA DA 3 GShortage2025-12-222026-11-30Problemi produttivi
🇬🇷 GRPROSTIN E2 VAG.TAB 3MG/TAB ΒΤX4Limited availability2025-12-152027-02-26Delivery delay
🇩🇪 DEMinprostin E2 Vaginalgel 2mgShortage2025-12-012026-11-30Probleme beim Wirkstoffhersteller
🇮🇹 ITPREPIDIL — 2 MG/3 G GEL VAGINALE, 1 SIRINGA PRERIEMPITA 3 GShortage2025-10-062026-12-30Problemi produttivi
🇦🇹 ATProstin E2 3 mg - Vaginaltabletten (PZN 1106746)Shortage2025-07-302026-10-15Verzögerung bei der Herstellung
🇩🇪 DEMinprostin E2 VaginaltablettenShortage2025-07-212027-02-28Sonstige

Frequently asked

Is Dinoproston currently in shortage in Europe?

Yes. As of 14 November 2026 (Greece: list dated 31 October 2026, posted 9 November 2026), availability issues are reported in: Austria, Germany, Greece, Italy, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.

When is the Dinoproston shortage expected to end?

Agency prognoses on file range from 2026-11-30 to 2027-02-28. Such dates are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.

Are there alternatives to Dinoproston?

5 of the open register entries note alternatives, equivalents or another supply route (for example the same active substance from another maker, an alternative treatment or an import). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Dinoproston availability data come from?

Directly from the official medicines-agency registers that list Dinoproston: BASG (Austria), BfArM (Germany), ANSM (France), EOF limited-availability list (Greece), AIFA (Italy), Läkemedelsverket (Sweden). Every row on this page links to the official register it comes from (to the record itself where the register has a page for each record), and the day each register was read is shown on this page. Names appear as each register spells them, so the same substance can also appear under another spelling on a separate page.

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the status of Dinoproston — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/dinoprostone/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Dinoproston availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/dinoprostone/" rel="nofollow">Dinoproston shortage status — European Medicine Shortage Tracker</a> by Mobi Doctor</p>
Cite: “Dinoproston: availability status in 6 European registers — European Medicine Shortage Tracker (Mobi Doctor), registers read 14 November 2026 (Greece: list dated 31 October 2026, posted 9 November 2026).” Link this page and the agency record. Statuses come from the linked official registers and can change after the read date shown.