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Dinoprostone currently has availability issues reported in 7 European registers: Austria, Germany, France, Greece, Ireland, Italy, Sweden.
Shortage ATC G02AD02 · also listed as: DINOPROSTON · dinoprostone · data refreshed 7 August 2026
As of 7 August 2026, 7 of the 10 tracked registers list current availability issues for Dinoprostone, covering 15 affected product presentations. The longest-running open report was filed in Germany on 2025-07-21 and has now been open for about 13 months. Where agencies state a cause, manufacturing problems lead with 5 of the 8 stated-cause reports, followed by unexpectedly high demand with 1. The furthest expected-resolution date currently on file is 2026-10-31; the earliest is 2026-08-07. The issue spread across registers over time rather than at once: Germany reported first (2025-07-21), with Ireland following roughly 8 months later — a pattern typical of supply problems cascading between national markets. Registers in Germany, Greece, Ireland, Italy, Sweden indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Dinoprostone is coded G02AD02 — a medicine acting on the genito-urinary system and sex hormones — so clinically related products appear under “Related medicines” below.
| Where | Status & products | Since | Expected end | Reason / alternatives | Source |
|---|---|---|---|---|---|
| 🇦🇹 Austria | Shortage Prepidil - Gel zur intrazervikalen Anwendung + 1 more productsProstin E2 3 mg - Vaginaltabletten | 2025-07-30 | — | — | register ↗ |
| 🇩🇪 Germany | Shortage Minprostin E2 Vaginalgel 1mg + 3 more productsMinprostin E2 Vaginalgel 2mg Minprostin E2 Vaginaltabletten Prepidil Gel | 2025-07-21 | 2026-10-31 | Probleme beim Wirkstoffhersteller Alternatives: N/A | register ↗ |
| 🇫🇷 France | Limited availability Prostine E2 1 mg/3 g, gel vaginal | — | — | Gynécologie | register ↗ |
| 🇬🇷 Greece | Limited availability Dinoproston + 1 more productsPROSTIN E2 VAG.TAB 3MG/TAB ΒΤX4 | 2025-12-15 | 2026-08-31 | Ν Ι.Φ.Ε.Τ. ΕΡΕΥΝΑ ΑΓΟΡΑΣ Alternatives: ΑΝΑΜΕΝΕΤΑΙ | register ↗ |
| 🇮🇪 Ireland | Shortage Prostin E2 1 mg Vaginal Gel | 2026-03-27 | 2026-08-07 | API shortage/unavailability (Global) Alternatives: Alternative(s) available — see the national register. | register ↗ |
| 🇮🇹 Italy | Shortage PREPIDIL + 2 more productsPREPIDIL PREPIDIL | 2025-10-06 | 2026-10-31 | Problemi produttivi Alternatives: AIFA: import of a foreign equivalent can be authorised. | register ↗ |
| 🇸🇪 Sweden | Shortage Minprostin 1 mg Vaginalgel + 1 more productsMinprostin 2 mg Vaginalgel | 2026-01-19 | 2026-10-23 | — Alternatives: Alternative(s) available — see the national register. | register ↗ |
Every individual register entry for Dinoprostone in the tracked sources, newest first — including resolved and discontinued reports.
| Reg. | Product | Status | Reported | Expected end | Stated reason |
|---|---|---|---|---|---|
| 🇬🇷 GR | Dinoproston | Limited availability | 2026-07-03 | 2026-08-20 | Ν Ι.Φ.Ε.Τ. ΕΡΕΥΝΑ ΑΓΟΡΑΣ |
| 🇮🇹 IT | PREPIDIL | Shortage | 2026-04-30 | 2026-10-31 | Problemi produttivi |
| 🇸🇪 SE | Minprostin 2 mg Vaginalgel | Shortage | 2026-03-30 | 2026-10-23 | |
| 🇮🇪 IE | Prostin E2 1 mg Vaginal Gel | Shortage | 2026-03-27 | 2026-08-07 | API shortage/unavailability (Global) |
| 🇩🇪 DE | Prepidil Gel | Shortage | 2026-01-23 | 2026-10-31 | Erhöhte Nachfrage |
| 🇸🇪 SE | Minprostin 1 mg Vaginalgel | Shortage | 2026-01-19 | 2026-10-09 | |
| 🇦🇹 AT | Prepidil - Gel zur intrazervikalen Anwendung | Shortage | 2025-12-22 | — | |
| 🇮🇹 IT | PREPIDIL | Shortage | 2025-12-22 | 2026-10-31 | Problemi produttivi |
| 🇬🇷 GR | PROSTIN E2 VAG.TAB 3MG/TAB ΒΤX4 | Limited availability | 2025-12-15 | 2026-08-31 | PFIZER ΕΛΛΑΣ Α.Ε. Καθυστέρηση παράδοσης Εναλλακτικά μέσω έκτ |
| 🇩🇪 DE | Minprostin E2 Vaginalgel 1mg | Shortage | 2025-12-01 | 2026-10-31 | Probleme beim Wirkstoffhersteller |
| 🇩🇪 DE | Minprostin E2 Vaginalgel 2mg | Shortage | 2025-12-01 | 2026-09-30 | Probleme beim Wirkstoffhersteller |
| 🇮🇹 IT | PREPIDIL | Shortage | 2025-10-06 | 2026-10-31 | Problemi produttivi |
| 🇦🇹 AT | Prostin E2 3 mg - Vaginaltabletten | Shortage | 2025-07-30 | — | |
| 🇩🇪 DE | Minprostin E2 Vaginaltabletten | Shortage | 2025-07-21 | 2026-10-31 | Sonstige |
| 🇫🇷 FR | Prostine E2 1 mg/3 g, gel vaginal | Limited availability | — | — | Gynécologie |
Yes. As of 7 August 2026, availability issues are reported in: Austria, Germany, France, Greece, Ireland, Italy, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.
Agency prognoses on file range from 2026-08-07 to 2026-10-31. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.
12 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.
Directly from the official medicines-agency registers that list Dinoprostone: BASG (Austria), BfArM (Germany), ANSM (France), EOF limited-availability list (Greece), HPRA (Ireland), AIFA (Italy), Läkemedelsverket (Sweden). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.
Pharmacies, patient sites and newsrooms are welcome to embed the live status of Dinoprostone — free, with attribution. Copy this snippet:
<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/dinoprostone/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Dinoprostone availability in Europe"></iframe> <p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/dinoprostone/">Dinoprostone shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>