What To Know About “Ozempic Face"

What Is Ozempic Face?

“Ozempic face” describes sagging, aged skin that can appear after rapid weight loss with semaglutide (Ozempic). Facial fat loss reduces elasticity and may cause wrinkles, hollowing, or sagging. Doctors may recommend fillers, lifestyle changes, or adjusting medication.

What To Know About “Ozempic Face"
Medically reviewed

Dr. Chrysoula I. Liakou MD, PhD Google Scholar LinkedIn

Internal Medicine Specialist
Cancer Immunology Researcher

What Is “Ozempic Face”?


A condition known as “Ozempic face” may occur due to the type 2 diabetes medication semaglutide (Ozempic). This can cause the skin on the face to become saggy and aged-looking. To address this, a doctor may suggest changing the patient's lifestyle or suggest facial fillers as a treatment option.


Ozempic is a prescription-only medication approved for diabetes, but is often used by people to achieve a desired body weight. It should be injected once a week at the same site, preferably in the thigh, upper arm, or abdomen, as recommended by healthcare professionals.


This article provides an overview of the “Ozempic face,” including an explanation of how Ozempic can affect the face, other potential side effects of the medication, and ways to mitigate the facial effects of Ozempic.



How Ozempic Causes Facial Changes


Ozempic, also known as semaglutide, belongs to a class of drugs called incretin mimetics. These drugs prompt the pancreas to release enough insulin when the blood sugar level is elevated.


Ozempic is a long-lasting and effective glucagon-like peptide-1 receptor agonist. This helps to reduce a person's appetite, leading to lower food consumption and fewer calories consumed. Additionally, it delays gastric emptying, so the person feels fuller for a longer period.


Ozempic, when used under a doctor’s guidance, is generally safe; however, it can cause sudden weight loss, which may be particularly noticeable on the face.


Facial fat helps to protect the face and contributes to a youthful appearance. When weight is lost, the fat in the face decreases, leading to dermatological changes such as wrinkles and sagging skin. The lack of fat that previously stretched and cushioned the skin can cause the skin to appear less elastic.


Following a sudden decrease in weight, the skin of the face may become less resistant due to the reduction of elastin and collagen, two essential proteins for maintaining the skin's structural stability.


Consequently, people taking Ozempic may experience the following facial symptoms.

  • Heightened indications of ageing, such as an increase in lines and wrinkles.

  • Fat reduction, potentially resulting in skin laxity and sagging.

  • A sunken or hollow appearance.

  • Lipodystrophy impacts the body's fat accumulation and storage patterns.

 

Facial Changes Linked to “Ozempic Face”

Facial Effect Cause Possible Treatment
Wrinkles & fine lines Loss of skin elasticity Dermatological fillers, skincare
Sagging skin Reduced collagen & fat volume Protein-rich diet, fillers
Hollow cheeks Fat loss from rapid weight loss Fillers, healthy weight maintenance
Skin laxity Reduced elastin & hydration Hydration, lifestyle changes



Other Side Effects of Ozempic to Know


While Ozempic is safe, it can cause mild to severe side effects. There are several types of these:

  • Fatigue

  • Flatulence

  • Abdominal pain

  • Vomiting

  • Diarrhoea

  • Stomach ache

  • Constipation

  • Injection-site reactions

  • Nausea


It is also possible to experience severe adverse effects in rare cases.

  • Alterations in vision.

  • Renal issues or kidney problems.

  • Conditions affecting the gallbladder.

  • Serious allergic responses.

  • Elevated susceptibility to thyroid cancer.

  • Decreased blood sugar levels are referred to as hypoglycemia.

  • Pancreatic inflammation, also known as pancreatitis.


How to Prevent or Manage “Ozempic Face”


If someone taking Ozempic as a prescription medication is concerned about possible facial side effects, a doctor may recommend any of the following as a preventative measure.

  • Decreasing the prescribed dose.

  • Switching to an alternative medication.

  • Consuming 1-2 litres of water daily.

  • Enhancing protein consumption through a diet rich in proteins.

  • Utilising dermatological fillers.


Implementing lifestyle changes to sustain a healthy body weight


It typically takes around five weeks for Ozempic to be cleared entirely from a person's system once they discontinue its use.



What Happens to the Face After Stopping Ozempic?


In a study conducted in 2022, researchers investigated the effects of semaglutide treatment on body weight and metabolic risk factors in 1,961 participants. After one year, they found that discontinuing treatment could lead to a reversal of weight loss.


It is also possible to observe the following after stopping.

  • Blood sugar spikes

  • Increased cravings

  • An absence of side effects



When to See a Doctor About Ozempic Side Effects


If any severe side effects are experienced while taking Ozempic, it is essential to contact a doctor. A record of symptoms should be kept and discussed with the doctor. It is important to note that Ozempic comes with a boxed warning for the potential risk of thyroid cancer. Animal trials have shown that it can cause cancer, but it is unknown if humans are at risk.


If a person experiences any of the following symptoms after taking Ozempic, they should talk to their doctor:

  • Difficulty in swallowing.

  • A lump or discomfort in the neck.

  • Wheezing sounds.

  • Difficulty in breathing.

  • A progressively worsening hoarse voice.


Summary


Ozempic is an injectable medication that controls blood sugar levels in people with type 2 diabetes. It can also be prescribed to people who are overweight or obese for chronic weight management. Ozempic can cause rapid weight loss but may also lead to facial side effects, commonly referred to as the "Ozempic face."


Doctors should be contacted immediately if someone experiences severe side effects while taking Ozempic. In such cases, the doctor may stop prescribing the medication and recommend lifestyle changes. Taking Ozempic only as a healthcare provider recommends is essential for the best results.


Discontinuing the use of Ozempic may cause a person to experience increased food cravings, a lack of the usual side effects they experienced while taking it, and higher-than-normal blood sugar levels. Additionally, a person may regain any weight loss while taking the medication.


You can connect with one of our doctors at Mobi Doctor with the click of a button and get the care you need.



FAQ

It refers to facial sagging, wrinkles, or hollowing caused by rapid weight loss while taking semaglutide (Ozempic).

Losing facial fat reduces elasticity, leading to sagging skin and visible signs of ageing.

Yes. Staying hydrated, eating protein-rich foods, maintaining weight gradually, and considering dermatological fillers can help.

Facial fullness may partially return if weight is regained, but skin laxity may persist without treatment.

Nausea, constipation, fatigue, diarrhoea, and abdominal pain are common. Rare risks include pancreatitis and thyroid concerns.

Seek medical help if you experience severe abdominal pain, thyroid-related symptoms, or allergic reactions while taking Ozempic.

Yes. Services like MobiDoctor offer consultations for managing Ozempic side effects and safe weight loss plans.


Comments

Submit


Swipe up to see a Dr.

close