Mounjaro And Zepbound Can Help With Weight Loss In People With Long-Term Obesity

●     Recent research indicates that medications incorporating Trizepatide as a critical ingredient effectively promote weight loss, irrespective of the duration of individuals' weight issues.

●     Experts recommend the continued use of these medications over the long term to sustain successful weight management, emphasising that discontinuation may lead to weight regain.

●     The study's findings suggest that individuals can initiate weight loss efforts at any point, emphasising there is always time to embark on healthier weight management.

Weight loss medicines like Mounjaro and Zepbound have Trizepatide, which can help people slim down and shrink their waist size. This works for anyone, no matter how long they've been dealing with weight problems.

This information comes from research that will be presented at the European Congress on Obesity in Venice, Italy, this May. However, other experts have yet to fully examine the study.

Mounjaro was approved by the authorities in 2022 to help with type 2 diabetes, and Zepbound was approved in 2023 to help adults manage their weight. Zepbound is for those who are quite overweight or have a high body mass index (BMI) and also have other health issues tied to their weight.

Researchers looked at data from large studies, such as the SURMOUNT phase 3 trials, to understand how tirzepatide helps with weight loss.

They compared people taking tirzepatide to others who were given a placebo (a treatment with no active drug). They studied three different groups:

People who were overweight or obese and had health problems related to their weight but did not have type 2 diabetes.

●     People who were overweight or obese and had type 2 diabetes.

●     People without type 2 diabetes had either tried a 12-week intense diet and exercise program or had been taking tripeptide for 36 weeks.

●     The researchers also looked at how long these people had been dealing with weight issues, grouping them into those who had problems for 10 years or less, between 10 and 20 years, and more than 20 years.

They checked the participants' weight and waist size, especially those who lost 5%, 10%, 15%, 20%, and 25% of their body weight.

Here's what they found:

●     People who had weight issues for less than 10 years and took 10 mg of tirzepatide lost 21% of their body weight after 72 weeks. Those who had issues for 10 to 20 years lost 20%, and those with problems for over 20 years lost 23%.

●     In the group with type 2 diabetes taking 15 mg of tirzepatide, those with weight issues for less than 10 years lost 13% of their body weight, those with issues for 10 to 20 years lost 16%, and those with problems for over 20 years lost 17%.

●     Waist size reduction followed a similar pattern.

The researchers shared in a news release that tirzepatide consistently helped people lose weight and reduce waist size, no matter how long they had been dealing with weight issues. This was in line with what they saw across all the studies they looked at.

Experts say that weight loss drugs like tirzepatide work by affecting your hormones to help you shed pounds, and they did their job in recent studies. One thing to note, though, is that these medications are meant for long-term use. If someone stops taking them, there's a chance they could gain the weight back unless they've also made lasting changes to their diet and lifestyle while on the medication.

In a study from 2023, it was found that people who stopped taking the medication and were given a placebo instead gained back about 14% of their weight after 36 weeks. Meanwhile, those who stayed on the medication continued to lose weight, dropping an extra 5%.

However, not all insurance plans cover these medications, and there are some side effects to consider, like nausea, vomiting, and constipation. Doctors usually start patients on a low dose to help reduce these side effects.

Another point from the research is that the amount of weight loss was similar, no matter how long someone had been dealing with obesity. This suggests that it's never too late to start obesity treatment, and the science supports using these treatments for patients regardless of their initial body size or how long they've had obesity. Still, it's essential for each person's treatment plan to be tailored to their individual needs.

If you're looking for guidance on weight loss and managing obesity, Mobi Doctor can provide the support you need. Our team is ready to offer personalised advice and treatment options tailored to your unique health journey.