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Isoniazide, rifampicine shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Isoniazide, rifampicine currently has availability issues reported in 2 European registers: France, Italy.

Shortage  ATC — · also listed as: isoniazide, rifampicine · ISONIAZIDE + RIFAMPICINA · data refreshed 15 September 2026

Key facts

As of 15 September 2026, 2 of the 8 tracked registers list current availability issues for Isoniazide, rifampicine, covering 2 affected product presentations. The longest-running open report was filed in Italy on 2021-08-16 and has now been open for about 61 months. Where agencies state a cause, manufacturing problems lead with 1 of the 1 stated-cause reports. The furthest expected-resolution date currently on file is 2026-12-31; the earliest is 2026-12-31. Registers in Italy indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.

WhereStatus & productsSinceExpected end Reason / alternativesSource
🇫🇷 FranceLimited availability
Rifinah 300 mg/150 mg, comprimé enrobé
Infectiologieregister ↗
🇮🇹 ItalyShortage
RIFINAH
2021-08-162026-12-31Problemi produttivi: distribuzione contingentata
Alternatives: AIFA: import of a foreign equivalent can be authorised.
register ↗

Full report history (2 register entries)

Every individual register entry for Isoniazide, rifampicine in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇮🇹 ITRIFINAHShortage2021-08-162026-12-31Problemi produttivi: distribuzione contingentata
🇫🇷 FRRifinah 300 mg/150 mg, comprimé enrobéLimited availabilityInfectiologie

Frequently asked

Is Isoniazide, rifampicine currently in shortage in Europe?

Yes. As of 15 September 2026, availability issues are reported in: France, Italy. Availability is national — a shortage in one country does not mean it is short everywhere.

When is the Isoniazide, rifampicine shortage expected to end?

Agency prognoses on file range from 2026-12-31 to 2026-12-31. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.

Are there alternatives to Isoniazide, rifampicine?

1 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Isoniazide, rifampicine availability data come from?

Directly from the official medicines-agency registers that list Isoniazide, rifampicine: ANSM (France), AIFA (Italy). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the live status of Isoniazide, rifampicine — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/isoniazide-rifampicine/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Isoniazide, rifampicine availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/isoniazide-rifampicine/">Isoniazide, rifampicine shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Isoniazide, rifampicine: availability status across 2 European registers — European Medicine Shortage Tracker (MobiDoctor), 15 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.