← European Medicine Shortage Tracker · all medicines

Iloprost shortage — availability across Europe

Iloprost currently has availability issues reported in 1 European register: Italy.

MEDICALLY REVIEWED

Dr. Chrysoula I. Liakou MD, PhD

Internal Medicine Specialist
Cancer Immunology Researcher

Reviewed 30 July 2026 · next review due 30 January 2027

Shortage ATC — · also listed as: ILOPROST · data refreshed 7 August 2026

Key facts

As of 7 August 2026, Iloprost has active availability issues in 1 of 10 tracked European registers.
Registers reporting issues: Italy.
Longest-running open report: since 2024-09-16 (23 months, Italy).
Data source: 1 official medicines-agency register, refreshed daily.

As of 7 August 2026, 1 of the 10 tracked registers list current availability issues for Iloprost, covering 4 affected product presentations. The longest-running open report was filed in Italy on 2024-09-16 and has now been open for about 23 months. Where agencies state a cause, manufacturing problems lead with 2 of the 4 stated-cause reports, followed by commercial decisions or discontinuation with 1. Momentum is current, not historical: 2 of the open reports were filed within the last 90 days. Registers in Italy indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.

Where	Status & products	Since	Expected end	Reason / alternatives	Source
🇮🇹 Italy	Shortage ILOPROST RAFARM + 3 more products ILOPROST ZENTIVA ILOPROST ZENTIVA ILOPROST ZENTIVA ITALIA	2024-09-16	—	Cessata commercializzazione temporanea Alternatives: AIFA: equivalents with the same active substance are available.	register ↗

New register reports per month

Full report history (4 register entries)

Every individual register entry for Iloprost in the tracked sources, newest first — including resolved and discontinued reports.

Reg.	Product	Status	Reported	Expected end	Stated reason
🇮🇹 IT	ILOPROST RAFARM	Shortage	2026-07-10	—	Cessata commercializzazione temporanea
🇮🇹 IT	ILOPROST ZENTIVA	Shortage	2026-06-30	—	Problemi produttivi
🇮🇹 IT	ILOPROST ZENTIVA ITALIA	Shortage	2025-12-10	—	Problemi produttivi
🇮🇹 IT	ILOPROST ZENTIVA	Shortage	2024-09-16	—	Elevata richiesta

Frequently asked

Is Iloprost currently in shortage in Europe?

Yes. As of 7 August 2026, availability issues are reported in: Italy. Availability is national — a shortage in one country does not mean it is short everywhere.

Are there alternatives to Iloprost?

4 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Iloprost availability data come from?

Directly from the official medicines-agency register that lists Iloprost: AIFA (Italy). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the live status of Iloprost — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/iloprost/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Iloprost availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/iloprost/">Iloprost shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>

Cite: “Iloprost: availability status across 1 European registers — European Medicine Shortage Tracker (MobiDoctor), 7 August 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.