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1-({(5S,7S)-3-[5-(1-Hydroxy-1-methylethyl)-2-pyrazinyl]-7-methyl-2-oxo-1oxa-3-azaspiro[4.5]dec-7-yl}methyl)-1H-benzimidazole-6-carbonitrile + ACESULFAME + ACIDO CITRICO ANIDRO/MAGNESIO CARBONATO BASICO LEGGERO + AROMA ARANCIO/POMPELMO + AROMA LIMONE-PRUGNA + MAGNESIO PIDOLATO + SODIO BICARBONATO + SORBITOLO currently has availability issues reported in 1 European register: Italy.
Shortage ATC — · also listed as: 1-({(5S,7S)-3-[5-(1-Hydroxy-1-methylethyl)-2-pyrazinyl]-7-methyl-2-oxo-1oxa-3-azaspiro[4.5]dec-7-yl}methyl)-1H-benzimidazole-6-carbonitrile + ACESULFAME + ACIDO CITRICO ANIDRO/MAGNESIO CARBONATO BASICO LEGGERO + AROMA ARANCIO/POMPELMO + AROMA LIMONE-PRUGNA + MAGNESIO PIDOLATO + SODIO BICARBONATO + SORBITOLO · data refreshed 17 August 2026
As of 17 August 2026, 1 of the 10 tracked registers list current availability issues for 1-({(5S,7S)-3-[5-(1-Hydroxy-1-methylethyl)-2-pyrazinyl]-7-methyl-2-oxo-1oxa-3-azaspiro[4.5]dec-7-yl}methyl)-1H-benzimidazole-6-carbonitrile + ACESULFAME + ACIDO CITRICO ANIDRO/MAGNESIO CARBONATO BASICO LEGGERO + AROMA ARANCIO/POMPELMO + AROMA LIMONE-PRUGNA + MAGNESIO PIDOLATO + SODIO BICARBONATO + SORBITOLO, covering 1 affected product presentation. The longest-running open report was filed in Italy on 2025-06-05 and has now been open for about 14 months. Where agencies state a cause, commercial decisions or discontinuation lead with 1 of the 1 stated-cause reports. Registers in Italy indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.
| Where | Status & products | Since | Expected end | Reason / alternatives | Source |
|---|---|---|---|---|---|
| 🇮🇹 Italy | Shortage MAG 2 | 2025-06-05 | — | Motivi commerciali: cessata commercializzazione definitiva sul canale ospedaliero Alternatives: AIFA: equivalents with the same active substance are available. | register ↗ |
Every individual register entry for 1-({(5S,7S)-3-[5-(1-Hydroxy-1-methylethyl)-2-pyrazinyl]-7-methyl-2-oxo-1oxa-3-azaspiro[4.5]dec-7-yl}methyl)-1H-benzimidazole-6-carbonitrile + ACESULFAME + ACIDO CITRICO ANIDRO/MAGNESIO CARBONATO BASICO LEGGERO + AROMA ARANCIO/POMPELMO + AROMA LIMONE-PRUGNA + MAGNESIO PIDOLATO + SODIO BICARBONATO + SORBITOLO in the tracked sources, newest first — including resolved and discontinued reports.
| Reg. | Product | Status | Reported | Expected end | Stated reason |
|---|---|---|---|---|---|
| 🇮🇹 IT | MAG 2 | Shortage | 2025-06-05 | — | Motivi commerciali: cessata commercializzazione definitiva s |
Yes. As of 17 August 2026, availability issues are reported in: Italy. Availability is national — a shortage in one country does not mean it is short everywhere.
1 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.
Directly from the official medicines-agency register that lists 1-({(5S,7S)-3-[5-(1-Hydroxy-1-methylethyl)-2-pyrazinyl]-7-methyl-2-oxo-1oxa-3-azaspiro[4.5]dec-7-yl}methyl)-1H-benzimidazole-6-carbonitrile + ACESULFAME + ACIDO CITRICO ANIDRO/MAGNESIO CARBONATO BASICO LEGGERO + AROMA ARANCIO/POMPELMO + AROMA LIMONE-PRUGNA + MAGNESIO PIDOLATO + SODIO BICARBONATO + SORBITOLO: AIFA (Italy). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.
Pharmacies, patient sites and newsrooms are welcome to embed the live status of 1-({(5S,7S)-3-[5-(1-Hydroxy-1-methylethyl)-2-pyrazinyl]-7-methyl-2-oxo-1oxa-3-azaspiro[4.5]dec-7-yl}methyl)-1H-benzimidazole-6-carbonitrile + ACESULFAME + ACIDO CITRICO ANIDRO/MAGNESIO CARBONATO BASICO LEGGERO + AROMA ARANCIO/POMPELMO + AROMA LIMONE-PRUGNA + MAGNESIO PIDOLATO + SODIO BICARBONATO + SORBITOLO — free, with attribution. Copy this snippet:
<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/1-5s-7s-3-5-1-hydroxy-1-methylethyl-2-pyrazinyl-7-methyl-2-o/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="1-({(5S,7S)-3-[5-(1-Hydroxy-1-methylethyl)-2-pyrazinyl]-7-methyl-2-oxo-1oxa-3-azaspiro[4.5]dec-7-yl}methyl)-1H-benzimidazole-6-carbonitrile + ACESULFAME + ACIDO CITRICO ANIDRO/MAGNESIO CARBONATO BASICO LEGGERO + AROMA ARANCIO/POMPELMO + AROMA LIMONE-PRUGNA + MAGNESIO PIDOLATO + SODIO BICARBONATO + SORBITOLO availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/1-5s-7s-3-5-1-hydroxy-1-methylethyl-2-pyrazinyl-7-methyl-2-o/">1-({(5S,7S)-3-[5-(1-Hydroxy-1-methylethyl)-2-pyrazinyl]-7-methyl-2-oxo-1oxa-3-azaspiro[4.5]dec-7-yl}methyl)-1H-benzimidazole-6-carbonitrile + ACESULFAME + ACIDO CITRICO ANIDRO/MAGNESIO CARBONATO BASICO LEGGERO + AROMA ARANCIO/POMPELMO + AROMA LIMONE-PRUGNA + MAGNESIO PIDOLATO + SODIO BICARBONATO + SORBITOLO shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>