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Tiotepa currently has availability issues reported in 2 European registers: Italy, Sweden.
Shortage ATC — · also listed as: TIOTEPA · data refreshed 8 September 2026
As of 8 September 2026, 2 of the 9 tracked registers list current availability issues for Tiotepa, covering 4 affected product presentations. The longest-running open report was filed in Sweden on 2024-02-01 and has now been open for about 31 months. Where agencies state a cause, manufacturing problems lead with 2 of the 2 stated-cause reports. The furthest expected-resolution date currently on file is 2027-01-01; the earliest is 2027-01-01. Notably, 1 report has already passed the expected-resolution date without closing — prognoses for this medicine should be read as estimates, not commitments. Registers in Italy, Sweden indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.
| Where | Status & products | Since | Expected end | Reason / alternatives | Source |
|---|---|---|---|---|---|
| 🇮🇹 Italy | Shortage THIOTEPA MEDAC + 1 more productsTHIOTEPA MEDAC | 2024-09-15 | — | Problemi produttivi: forniture discontinue Alternatives: AIFA: equivalents with the same active substance are available. | register ↗ |
| 🇸🇪 Sweden | Shortage TEPADINA 400 mg Pulver och vätska till infusionsvätska, lösning + 1 more productsThiotepa Fresenius Kabi 100 mg Pulver till konc. till infusionsvätska, lösning | 2024-02-01 | 2027-01-01 | — Alternatives: Alternative(s) available — see the national register. | register ↗ |
Every individual register entry for Tiotepa in the tracked sources, newest first — including resolved and discontinued reports.
| Reg. | Product | Status | Reported | Expected end | Stated reason |
|---|---|---|---|---|---|
| 🇸🇪 SE | Thiotepa Fresenius Kabi 100 mg Pulver till konc. till infusionsvätska, | Shortage | 2026-07-05 | 2026-08-14 | |
| 🇮🇹 IT | THIOTEPA MEDAC | Shortage | 2024-10-01 | — | Problemi produttivi: forniture discontinue |
| 🇮🇹 IT | THIOTEPA MEDAC | Shortage | 2024-09-15 | — | Problemi produttivi: forniture discontinue |
| 🇸🇪 SE | TEPADINA 400 mg Pulver och vätska till infusionsvätska, lösning | Shortage | 2024-02-01 | 2027-01-01 |
Yes. As of 8 September 2026, availability issues are reported in: Italy, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.
Agency prognoses on file range from 2027-01-01 to 2027-01-01. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.
4 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.
Directly from the official medicines-agency registers that list Tiotepa: AIFA (Italy), Läkemedelsverket (Sweden). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.
Pharmacies, patient sites and newsrooms are welcome to embed the live status of Tiotepa — free, with attribution. Copy this snippet:
<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/tiotepa/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Tiotepa availability in Europe"></iframe> <p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/tiotepa/">Tiotepa shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>