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Pentoxifilina shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Pentoxifilina currently has availability issues reported in 3 European registers: Austria, Spain, Italy.

Shortage  ATC — · also listed as: PENTOXIFYLLIN · PENTOXIFILINA · PENTOXIFILLINA · data refreshed 5 September 2026

Key facts

As of 5 September 2026, 3 of the 9 tracked registers list current availability issues for Pentoxifilina, covering 4 affected product presentations. The longest-running open report was filed in Spain on 2025-12-04 and has now been open for about 9 months. The furthest expected-resolution date currently on file is 2027-01-01; the earliest is 2027-01-01. Momentum is current, not historical: 2 of the open reports were filed within the last 90 days. The issue spread across registers over time rather than at once: Spain reported first (2025-12-04), with Italy following roughly 8 months later — a pattern typical of supply problems cascading between national markets. Registers in Spain, Italy indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.

WhereStatus & productsSinceExpected end Reason / alternativesSource
🇦🇹 AustriaShortage
Pentomer retard 400 mg - Filmtabletten
+ 1 more products
Pentomer retard 600 mg - Filmtabletten
2025-12-10register ↗
🇪🇸 SpainShortage
PENTOXIFILINA ALTER 400 mg COMPRIMIDOS DE LIBERACION PROLONGADA EFG, 60 comprimidos
2025-12-04Existen otros medicamentos con el mismo principio activo y misma vía.
Alternatives: Existe/n otro/s medicamento/s con el mismo principio activo y para la misma vía de administración.
register ↗
🇮🇹 ItalyShortage
TRENTAL
2026-08-152027-01-01Problemi regolatori: ridotta disponibilità
Alternatives: AIFA: an alternative treatment is available (ask your doctor).
register ↗

New register reports per month

2025-12: 22026-01: 02026-02: 02026-03: 02026-04: 02026-05: 02026-06: 12026-07: 02026-08: 12025-122026-08

Full report history (4 register entries)

Every individual register entry for Pentoxifilina in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇮🇹 ITTRENTALShortage2026-08-152027-01-01Problemi regolatori: ridotta disponibilità
🇦🇹 ATPentomer retard 600 mg - FilmtablettenLimited availability2026-06-18
🇦🇹 ATPentomer retard 400 mg - FilmtablettenShortage2025-12-10
🇪🇸 ESPENTOXIFILINA ALTER 400 mg COMPRIMIDOS DE LIBERACION PROLONGADA EFG, 6Shortage2025-12-04Existen otros medicamentos con el mismo principio activo y m

Frequently asked

Is Pentoxifilina currently in shortage in Europe?

Yes. As of 5 September 2026, availability issues are reported in: Austria, Spain, Italy. Availability is national — a shortage in one country does not mean it is short everywhere.

When is the Pentoxifilina shortage expected to end?

Agency prognoses on file range from 2027-01-01 to 2027-01-01. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.

Are there alternatives to Pentoxifilina?

2 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Pentoxifilina availability data come from?

Directly from the official medicines-agency registers that list Pentoxifilina: BASG (Austria), AEMPS CIMA (Spain), AIFA (Italy). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the live status of Pentoxifilina — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/pentoxifilina/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Pentoxifilina availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/pentoxifilina/">Pentoxifilina shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Pentoxifilina: availability status across 3 European registers — European Medicine Shortage Tracker (MobiDoctor), 5 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.