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Misoprostol currently has availability issues reported in 2 European registers: Ireland, Italy.
Shortage ATC — · also listed as: Misoprostol · MISOPROSTOLO · data refreshed 9 September 2026
As of 9 September 2026, 2 of the 9 tracked registers list current availability issues for Misoprostol, covering 2 affected product presentations. The longest-running open report was filed in Italy on 2017-11-30 and has now been open for about 106 months. Where agencies state a cause, unexpectedly high demand lead with 1 of the 2 stated-cause reports, followed by commercial decisions or discontinuation with 1. Notably, 1 report has already passed the expected-resolution date without closing — prognoses for this medicine should be read as estimates, not commitments. Registers in Ireland, Italy indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.
| Where | Status & products | Since | Expected end | Reason / alternatives | Source |
|---|---|---|---|---|---|
| 🇮🇪 Ireland | Shortage Cytotec 200 microgram tablets | 2026-05-18 | 2026-08-15 | Unexpected increased demand (Ireland only) Alternatives: Alternative(s) available — see the national register. | register ↗ |
| 🇮🇹 Italy | Shortage MISOONE | 2017-11-30 | — | Cessata commercializzazione definitiva Alternatives: AIFA: import of a foreign equivalent can be authorised. | register ↗ |
Every individual register entry for Misoprostol in the tracked sources, newest first — including resolved and discontinued reports.
| Reg. | Product | Status | Reported | Expected end | Stated reason |
|---|---|---|---|---|---|
| 🇮🇪 IE | Cytotec 200 microgram tablets | Shortage | 2026-05-18 | 2026-08-15 | Unexpected increased demand (Ireland only) |
| 🇮🇹 IT | MISOONE | Shortage | 2017-11-30 | — | Cessata commercializzazione definitiva |
Yes. As of 9 September 2026, availability issues are reported in: Ireland, Italy. Availability is national — a shortage in one country does not mean it is short everywhere.
2 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.
Directly from the official medicines-agency registers that list Misoprostol: HPRA (Ireland), AIFA (Italy). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.
Pharmacies, patient sites and newsrooms are welcome to embed the live status of Misoprostol — free, with attribution. Copy this snippet:
<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/misoprostol/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Misoprostol availability in Europe"></iframe> <p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/misoprostol/">Misoprostol shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>