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Metotrexato sodico shortage — availability across Europe

Name: European Medicine Shortage Tracker dataset
Creator: MobiDoctor
License: https://creativecommons.org/licenses/by/4.0/

Availability information only — Mobi Doctor doesn't sell medicines; check with a pharmacy.

MEDICALLY REVIEWED

Dr. Chrysoula I. Liakou MD, PhD

Internal Medicine Specialist
Cancer Immunology Researcher

Reviewed 30 July 2026 · next review due 30 January 2027

Metotrexato sodico currently has availability issues reported in 1 European register: Italy.

Shortage ATC — · also listed as: METOTREXATO SODICO · data refreshed 8 September 2026

Key facts

As of 8 September 2026, Metotrexato sodico has active availability issues in 1 of 9 tracked European registers.
Registers reporting issues: Italy.
Longest-running open report: since 2021-06-22 (63 months, Italy).
Data source: 1 official medicines-agency register, refreshed daily.

As of 8 September 2026, 1 of the 9 tracked registers list current availability issues for Metotrexato sodico, covering 3 affected product presentations. The longest-running open report was filed in Italy on 2021-06-22 and has now been open for about 63 months. Where agencies state a cause, manufacturing problems lead with 3 of the 3 stated-cause reports. Registers in Italy indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.

Where	Status & products	Since	Expected end	Reason / alternatives	Source
🇮🇹 Italy	Shortage METHOTREXATE + 2 more products METHOTREXATE METHOTREXATE	2021-06-22	—	Problemi produttivi Alternatives: AIFA: import of a foreign equivalent can be authorised.	register ↗

Full report history (3 register entries)

Every individual register entry for Metotrexato sodico in the tracked sources, newest first — including resolved and discontinued reports.

Reg.	Product	Status	Reported	Expected end	Stated reason
🇮🇹 IT	METHOTREXATE	Shortage	2022-03-31	—	Problemi produttivi
🇮🇹 IT	METHOTREXATE	Shortage	2021-11-15	—	Problemi produttivi
🇮🇹 IT	METHOTREXATE	Shortage	2021-06-22	—	Problemi produttivi

Frequently asked

Is Metotrexato sodico currently in shortage in Europe?

Yes. As of 8 September 2026, availability issues are reported in: Italy. Availability is national — a shortage in one country does not mean it is short everywhere.

Are there alternatives to Metotrexato sodico?

3 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Metotrexato sodico availability data come from?

Directly from the official medicines-agency register that lists Metotrexato sodico: AIFA (Italy). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the live status of Metotrexato sodico — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/metotrexato-sodico/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Metotrexato sodico availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/metotrexato-sodico/">Metotrexato sodico shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>

Cite: “Metotrexato sodico: availability status across 1 European registers — European Medicine Shortage Tracker (MobiDoctor), 8 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.