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Fluorouracil shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Fluorouracil currently has availability issues reported in 3 European registers: Spain, Greece, Sweden.

Shortage  ATC L01BC02 · also listed as: FLUOROURACILO · fluorouracil · data refreshed 14 September 2026

Key facts

As of 14 September 2026, 3 of the 9 tracked registers list current availability issues for Fluorouracil, covering 3 affected product presentations. The longest-running open report was filed in Sweden on 2025-01-30 and has now been open for about 20 months. Where agencies state a cause, delivery delays lead with 1 of the 1 stated-cause reports. The furthest expected-resolution date currently on file is 2026-12-31; the earliest is 2026-11-30. The issue spread across registers over time rather than at once: Sweden reported first (2025-01-30), with Spain following roughly 18 months later — a pattern typical of supply problems cascading between national markets. Registers in Spain, Greece, Sweden indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Fluorouracil is coded L01BC02 — a medicine acting on antineoplastic and immunomodulating agents — so clinically related products appear under “Related medicines” below.

Resolved Listed in the EMA shortages catalogue — EU-level issue. EMA record ↗
WhereStatus & productsSinceExpected end Reason / alternativesSource
🇪🇺 EU-wide (EMA)Resolved
Fluorouracil
2024-08-06Cancer;Neoplasmsregister ↗
🇪🇸 SpainShortage
FLUOROURACILO ACCORD 50 mg/ml SOLUCION INYECTABLE O PARA PERFUSION EFG, 1 vial de 100 ml
2026-07-072026-12-30Se puede solicitar como medicamento extranjero.
Alternatives: Se puede solicitar como medicamento extranjero.
register ↗
🇬🇷 GreeceLimited availability
FLUOROURACIL
2025-02-172026-11-30OPUS MATERIA ΕΠΕ Καθυστέρηση παράδοσης Εναλλακτικά άλλο σκεύασμα της ί
Alternatives: Προβλήματα στην παραγωγική
register ↗
🇸🇪 SwedenShortage
Fluorouracil Teva 50 mg/ml Injektionsvätska, lösning
2025-01-302026-12-31
Alternatives: Alternative(s) available — see the national register.
register ↗

New register reports per month

2024-08: 12024-09: 02024-10: 02024-11: 02024-12: 02025-01: 12025-02: 12025-03: 02025-04: 02025-05: 02025-06: 02025-07: 02025-08: 02025-09: 02025-10: 02025-11: 02025-12: 02026-01: 02026-02: 02026-03: 02026-04: 02026-05: 02026-06: 02026-07: 12024-082026-07

Full report history (4 register entries)

Every individual register entry for Fluorouracil in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇪🇸 ESFLUOROURACILO ACCORD 50 mg/ml SOLUCION INYECTABLE O PARA PERFUSION EFGShortage2026-07-072026-12-30Se puede solicitar como medicamento extranjero.
🇬🇷 GRFLUOROURACILLimited availability2025-02-172026-11-30OPUS MATERIA ΕΠΕ Καθυστέρηση παράδοσης Εναλλακτικά άλλο σκεύ
🇸🇪 SEFluorouracil Teva 50 mg/ml Injektionsvätska, lösningShortage2025-01-302026-12-31
🇪🇺 EUFluorouracilResolved2024-08-06Cancer;Neoplasms

Frequently asked

Is Fluorouracil currently in shortage in Europe?

Yes. As of 14 September 2026, availability issues are reported in: Spain, Greece, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.

When is the Fluorouracil shortage expected to end?

Agency prognoses on file range from 2026-11-30 to 2026-12-31. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.

Are there alternatives to Fluorouracil?

3 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Fluorouracil availability data come from?

Directly from the official medicines-agency registers that list Fluorouracil: AEMPS CIMA (Spain), EMA shortages catalogue (EU), EOF limited-availability list (Greece), Läkemedelsverket (Sweden). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Related medicines (same ATC class)

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the live status of Fluorouracil — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/fluorouracil/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Fluorouracil availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/fluorouracil/">Fluorouracil shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Fluorouracil: availability status across 4 European registers — European Medicine Shortage Tracker (MobiDoctor), 14 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.