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Concentrate of proteolytic enzymes enriched in bromelain shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Concentrate of proteolytic enzymes enriched in bromelain currently has availability issues reported in 1 European register: EU-wide.

Shortage  ATC — · also listed as: concentrate of proteolytic enzymes enriched in bromelain · data refreshed 13 September 2026

Key facts

As of 13 September 2026, 1 of the 9 tracked registers list current availability issues for Concentrate of proteolytic enzymes enriched in bromelain, covering 1 affected product presentation. The longest-running open report was filed in the EMA catalogue on 2026-05-06 and has now been open for about 4 months. Registers in EU-wide indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.

Shortage Listed in the EMA shortages catalogue — EU-level issue. EMA lists no available alternatives. EMA record ↗
WhereStatus & productsSinceExpected end Reason / alternativesSource
🇪🇺 EU-wide (EMA)Shortage
NexoBrid (concentrate of proteolytic enzymes enriched in bromelain)
2026-05-06Debridement
Alternatives: EMA lists no available alternatives.
register ↗

Full report history (1 register entry)

Every individual register entry for Concentrate of proteolytic enzymes enriched in bromelain in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇪🇺 EUNexoBrid (concentrate of proteolytic enzymes enriched in bromelain)Shortage2026-05-06Debridement

Frequently asked

Is Concentrate of proteolytic enzymes enriched in bromelain currently in shortage in Europe?

Yes. As of 13 September 2026, availability issues are reported in: EU-wide (EMA). Availability is national — a shortage in one country does not mean it is short everywhere.

Are there alternatives to Concentrate of proteolytic enzymes enriched in bromelain?

1 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Concentrate of proteolytic enzymes enriched in bromelain availability data come from?

Directly from the official medicines-agency register that lists Concentrate of proteolytic enzymes enriched in bromelain: EMA shortages catalogue (EU). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Embed this tracker

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<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/concentrate-of-proteolytic-enzymes-enriched-in-bromelain/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Concentrate of proteolytic enzymes enriched in bromelain availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/concentrate-of-proteolytic-enzymes-enriched-in-bromelain/">Concentrate of proteolytic enzymes enriched in bromelain shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Concentrate of proteolytic enzymes enriched in bromelain: availability status across 1 European registers — European Medicine Shortage Tracker (MobiDoctor), 13 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.