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Busulfan currently has availability issues reported in 2 European registers: Germany, Spain.
Shortage ATC L01AB01 · also listed as: Busulfan · BUSULFANO · data refreshed 10 September 2026
As of 10 September 2026, 2 of the 9 tracked registers list current availability issues for Busulfan, covering 2 affected product presentations. The longest-running open report was filed in Germany on 2026-01-01 and has now been open for about 8 months. Where agencies state a cause, manufacturing problems lead with 1 of the 1 stated-cause reports. The furthest expected-resolution date currently on file is 2026-10-21; the earliest is 2026-10-21. Registers in Germany, Spain indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Busulfan is coded L01AB01 — a medicine acting on antineoplastic and immunomodulating agents — so clinically related products appear under “Related medicines” below.
| Where | Status & products | Since | Expected end | Reason / alternatives | Source |
|---|---|---|---|---|---|
| 🇩🇪 Germany | Shortage Busulfan-ratiopharm 6 mg/ml Konzentrat zur Herstellung einer Infusionslösung | 2026-01-01 | 2026-10-21 | Probleme in der Herstellung Alternatives: N/A | register ↗ |
| 🇪🇸 Spain | Shortage BUSULFANO ASPEN 2 MG COMPRIMIDOS RECUBIERTOS CON PELICULA, 100 comprimidos | 2026-07-29 | — | Se puede solicitar como medicamento extranjero. Alternatives: Se puede solicitar como medicamento extranjero. | register ↗ |
Every individual register entry for Busulfan in the tracked sources, newest first — including resolved and discontinued reports.
| Reg. | Product | Status | Reported | Expected end | Stated reason |
|---|---|---|---|---|---|
| 🇪🇸 ES | BUSULFANO ASPEN 2 MG COMPRIMIDOS RECUBIERTOS CON PELICULA, 100 comprim | Shortage | 2026-07-29 | — | Se puede solicitar como medicamento extranjero. |
| 🇩🇪 DE | Busulfan-ratiopharm 6 mg/ml Konzentrat zur Herstellung einer Infusions | Shortage | 2026-01-01 | 2026-10-21 | Probleme in der Herstellung |
Yes. As of 10 September 2026, availability issues are reported in: Germany, Spain. Availability is national — a shortage in one country does not mean it is short everywhere.
Agency prognoses on file range from 2026-10-21 to 2026-10-21. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.
2 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.
Directly from the official medicines-agency registers that list Busulfan: BfArM (Germany), AEMPS CIMA (Spain). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.
Pharmacies, patient sites and newsrooms are welcome to embed the live status of Busulfan — free, with attribution. Copy this snippet:
<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/busulfan/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Busulfan availability in Europe"></iframe> <p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/busulfan/">Busulfan shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>