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Bortezomib shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Bortezomib currently has availability issues reported in 4 European registers: Spain, Greece, Italy, Sweden.

Shortage  ATC L01XG01 · also listed as: BORTEZOMIB · data refreshed 10 September 2026

Key facts

As of 10 September 2026, 4 of the 9 tracked registers list current availability issues for Bortezomib, covering 9 affected product presentations. The longest-running open report was filed in Spain on 2024-01-31 and has now been open for about 32 months. Where agencies state a cause, delivery delays lead with 2 of the 5 stated-cause reports, followed by manufacturing problems with 1. The furthest expected-resolution date currently on file is 2027-07-27; the earliest is 2026-10-14. Notably, 2 reports have already passed the expected-resolution date without closing — prognoses for this medicine should be read as estimates, not commitments. Momentum is current, not historical: 3 of the open reports were filed within the last 90 days. The issue spread across registers over time rather than at once: Spain reported first (2024-01-31), with Sweden following roughly 29 months later — a pattern typical of supply problems cascading between national markets. Registers in Spain, Greece, Italy, Sweden indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Bortezomib is coded L01XG01 — a medicine acting on antineoplastic and immunomodulating agents — so clinically related products appear under “Related medicines” below.

WhereStatus & productsSinceExpected end Reason / alternativesSource
🇪🇸 SpainShortage
BORTEZOMIB ACCORD 2,5 MG/ML SOLUCION INYECTABLE, 1 vial de 1 ml
+ 2 more products
BORTEZOMIB DR. REDDYS 3,5 MG POLVO PARA SOLUCION INYECTABLE EFG, 1 vial
BORTEZOMIB WAVERLEY 3,5 MG POLVO PARA SOLUCION INYECTABLE EFG, 1 vial
2024-01-312027-07-27Existen otros medicamentos con el mismo principio activo y misma vía.
Alternatives: Existe/n otro/s medicamento/s con el mismo principio activo y para la misma vía de administración.
register ↗
🇬🇷 GreeceLimited availability
BORTEZOMIB
+ 1 more products
BOTEVIA PD.INJ.SOL 3.5MG/VIAL BT x 1 VIAL
2025-04-092027-01-26Καθυστέρηση παράδοσης περιεκτικότητας Εναλλακτικά άλλα σκευάσματα της
Alternatives: Προβλήματα στην παραγωγική
register ↗
🇮🇹 ItalyShortage
BORTEZOMIB AUROBINDO
+ 2 more products
BORTEZOMIB DR. REDDY'S
BORTEZOMIB MEDAC
2025-07-10Elevata richiesta/problemi produttivi
Alternatives: AIFA: equivalents with the same active substance are available.
register ↗
🇸🇪 SwedenShortage
Bortezomib Accord 2,5 mg/ml Injektionsvätska, lösning
2026-06-202026-07-31
Alternatives: Alternative(s) available — see the national register.
register ↗

New register reports per month

2024-01: 12024-02: 02024-03: 02024-04: 02024-05: 02024-06: 02024-07: 02024-08: 02024-09: 02024-10: 02024-11: 02024-12: 02025-01: 02025-02: 02025-03: 02025-04: 12025-05: 02025-06: 02025-07: 12025-08: 02025-09: 02025-10: 02025-11: 02025-12: 02026-01: 02026-02: 02026-03: 12026-04: 12026-05: 12026-06: 22026-07: 02026-08: 12024-012026-08

Full report history (9 register entries)

Every individual register entry for Bortezomib in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇪🇸 ESBORTEZOMIB WAVERLEY 3,5 MG POLVO PARA SOLUCION INYECTABLE EFG, 1 vialShortage2026-08-162027-07-27Existen otros medicamentos con el mismo principio activo y m
🇪🇸 ESBORTEZOMIB DR. REDDYS 3,5 MG POLVO PARA SOLUCION INYECTABLE EFG, 1 viaShortage2026-06-302026-10-14
🇸🇪 SEBortezomib Accord 2,5 mg/ml Injektionsvätska, lösningShortage2026-06-202026-07-31
🇮🇹 ITBORTEZOMIB DR. REDDY'SShortage2026-05-31Elevata richiesta: forniture discontinue
🇮🇹 ITBORTEZOMIB AUROBINDOShortage2026-04-24Elevata richiesta/problemi produttivi
🇬🇷 GRBOTEVIA PD.INJ.SOL 3.5MG/VIAL BT x 1 VIALLimited availability2026-03-122026-07-31Καθυστέρηση παράδοσης περιεκτικότητας TOPOCAN PD.C.SO.IN 4mg
🇮🇹 ITBORTEZOMIB MEDACShortage2025-07-10Motivi commerciali
🇬🇷 GRBORTEZOMIBLimited availability2025-04-092027-01-26Καθυστέρηση παράδοσης περιεκτικότητας Εναλλακτικά άλλα σκευά
🇪🇸 ESBORTEZOMIB ACCORD 2,5 MG/ML SOLUCION INYECTABLE, 1 vial de 1 mlShortage2024-01-312026-10-29Existen otros medicamentos con el mismo principio activo y m

Frequently asked

Is Bortezomib currently in shortage in Europe?

Yes. As of 10 September 2026, availability issues are reported in: Spain, Greece, Italy, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.

When is the Bortezomib shortage expected to end?

Agency prognoses on file range from 2026-10-14 to 2027-07-27. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.

Are there alternatives to Bortezomib?

7 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Bortezomib availability data come from?

Directly from the official medicines-agency registers that list Bortezomib: AEMPS CIMA (Spain), EOF limited-availability list (Greece), AIFA (Italy), Läkemedelsverket (Sweden). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Related medicines (same ATC class)

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the live status of Bortezomib — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/bortezomib/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Bortezomib availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/bortezomib/">Bortezomib shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Bortezomib: availability status across 4 European registers — European Medicine Shortage Tracker (MobiDoctor), 10 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.