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Bendamustinhydrochlorid-Monohydrat shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Bendamustinhydrochlorid-Monohydrat currently has availability issues reported in 3 European registers: Germany, Spain, Sweden.

Shortage  ATC L01AA09 · also listed as: Bendamustinhydrochlorid-Monohydrat · BENDAMUSTINA · bendamustinhydroklorid · data refreshed 13 September 2026

Key facts

As of 13 September 2026, 3 of the 9 tracked registers list current availability issues for Bendamustinhydrochlorid-Monohydrat, covering 8 affected product presentations. The longest-running open report was filed in Germany on 2022-05-01 and has now been open for about 52 months. The furthest expected-resolution date currently on file is 2026-12-31; the earliest is 2026-11-29. Notably, 1 report has already passed the expected-resolution date without closing — prognoses for this medicine should be read as estimates, not commitments. The issue spread across registers over time rather than at once: Germany reported first (2022-05-01), with Sweden following roughly 49 months later — a pattern typical of supply problems cascading between national markets. Registers in Germany, Spain, Sweden indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching. In the WHO ATC classification, Bendamustinhydrochlorid-Monohydrat is coded L01AA09 — a medicine acting on antineoplastic and immunomodulating agents — so clinically related products appear under “Related medicines” below.

WhereStatus & productsSinceExpected end Reason / alternativesSource
🇩🇪 GermanyShortage
Bendamustin beta 180 mg/4 ml Konzentrat zur Herstellung einer Infusionslösung
2022-05-012026-12-31Sonstige
Alternatives: N/A
register ↗
🇪🇸 SpainShortage
BENDAMUSTINA ACCORD 2,5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCION PARA PERFUSION EFG , 5 viales de 100 mg
+ 5 more products
BENDAMUSTINA ACCORD 25 MG/ML CONCENTRADO PARA SOLUCION PARA PERFUSION , 5 viales de 4 ml
BENDAMUSTINA AUROVITAS 2.5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCION PARA PERFUSION EFG, 5 viales de 100 mg
BENDAMUSTINA BAXTER 2,5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCION PARA PERFUSION EFG 5 viales de 100 mg
BENDAMUSTINA DR. REDDYS 2,5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCION PARA PERFUSION EFG, 5 viales de 100 mg
BENDAMUSTINA DR. REDDYS 2,5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCION PARA PERFUSION EFG, 5 viales de 25 mg
2025-05-112026-12-30Existen otros medicamentos con el mismo principio activo y misma vía.
Alternatives: Existe/n otro/s medicamento/s con el mismo principio activo y para la misma vía de administración.
register ↗
🇸🇪 SwedenShortage
Bendamustine Accord 2,5 mg/ml Pulver till konc. till infusionsvätska, lösning
2026-06-012026-07-31
Alternatives: Alternative(s) available — see the national register.
register ↗

New register reports per month

2025-05: 12025-06: 22025-07: 02025-08: 02025-09: 02025-10: 12025-11: 02025-12: 02026-01: 02026-02: 12026-03: 02026-04: 02026-05: 12026-06: 12025-052026-06

Full report history (8 register entries)

Every individual register entry for Bendamustinhydrochlorid-Monohydrat in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇸🇪 SEBendamustine Accord 2,5 mg/ml Pulver till konc. till infusionsvätska, Shortage2026-06-012026-07-31
🇪🇸 ESBENDAMUSTINA ACCORD 25 MG/ML CONCENTRADO PARA SOLUCION PARA PERFUSION Shortage2026-05-192026-12-30Existen otros medicamentos con el mismo principio activo y m
🇪🇸 ESBENDAMUSTINA ACCORD 2,5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCION PARShortage2026-02-262026-12-30Existen otros medicamentos con el mismo principio activo y m
🇪🇸 ESBENDAMUSTINA AUROVITAS 2.5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCION Shortage2025-10-212026-11-29
🇪🇸 ESBENDAMUSTINA BAXTER 2,5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCION PARShortage2025-06-18
🇪🇸 ESBENDAMUSTINA DR. REDDYS 2,5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCIONShortage2025-06-03Existen otros medicamentos con el mismo principio activo y m
🇪🇸 ESBENDAMUSTINA DR. REDDYS 2,5 MG/ML POLVO PARA CONCENTRADO PARA SOLUCIONShortage2025-05-11Existen otros medicamentos con el mismo principio activo y m
🇩🇪 DEBendamustin beta 180 mg/4 ml Konzentrat zur Herstellung einer InfusionShortage2022-05-012026-12-31Sonstige

Frequently asked

Is Bendamustinhydrochlorid-Monohydrat currently in shortage in Europe?

Yes. As of 13 September 2026, availability issues are reported in: Germany, Spain, Sweden. Availability is national — a shortage in one country does not mean it is short everywhere.

When is the Bendamustinhydrochlorid-Monohydrat shortage expected to end?

Agency prognoses on file range from 2026-11-29 to 2026-12-31. These are manufacturer-reported estimates and frequently move; check the linked register entry for the latest date.

Are there alternatives to Bendamustinhydrochlorid-Monohydrat?

6 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Bendamustinhydrochlorid-Monohydrat availability data come from?

Directly from the official medicines-agency registers that list Bendamustinhydrochlorid-Monohydrat: BfArM (Germany), AEMPS CIMA (Spain), Läkemedelsverket (Sweden). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Related medicines (same ATC class)

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<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/bendamustinhydrochlorid-monohydrat/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Bendamustinhydrochlorid-Monohydrat availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/bendamustinhydrochlorid-monohydrat/">Bendamustinhydrochlorid-Monohydrat shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Bendamustinhydrochlorid-Monohydrat: availability status across 3 European registers — European Medicine Shortage Tracker (MobiDoctor), 13 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.