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Atovaquone + proguanil cloridrato shortage — availability across Europe

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MEDICALLY REVIEWED
Dr. Chrysoula I. Liakou MD, PhD
Internal Medicine Specialist
Cancer Immunology Researcher
Reviewed 30 July 2026 · next review due 30 January 2027

Atovaquone + proguanil cloridrato currently has availability issues reported in 1 European register: Italy.

Shortage  ATC — · also listed as: ATOVAQUONE + PROGUANIL CLORIDRATO · data refreshed 10 September 2026

Key facts

As of 10 September 2026, 1 of the 9 tracked registers list current availability issues for Atovaquone + proguanil cloridrato, covering 2 affected product presentations. The longest-running open report was filed in Italy on 2026-03-17 and has now been open for about 6 months. Where agencies state a cause, unexpectedly high demand lead with 1 of the 2 stated-cause reports, followed by manufacturing problems with 1. Registers in Italy indicate that alternatives or equivalents are available — a pharmacist or doctor can advise on switching.

WhereStatus & productsSinceExpected end Reason / alternativesSource
🇮🇹 ItalyShortage
ATOVAQUONE E PROGUANILE MYLAN GENERICS
+ 1 more products
MALARONE
2026-03-17Elevata richiesta
Alternatives: AIFA: equivalents with the same active substance are available.
register ↗

New register reports per month

2026-03: 12026-04: 02026-05: 02026-06: 02026-07: 02026-08: 02026-09: 12026-032026-09

Full report history (2 register entries)

Every individual register entry for Atovaquone + proguanil cloridrato in the tracked sources, newest first — including resolved and discontinued reports.

Reg.ProductStatusReportedExpected endStated reason
🇮🇹 ITMALARONEShortage2026-09-07Elevata richiesta/problemi produttivi: distribuzione conting
🇮🇹 ITATOVAQUONE E PROGUANILE MYLAN GENERICSShortage2026-03-17Elevata richiesta

Frequently asked

Is Atovaquone + proguanil cloridrato currently in shortage in Europe?

Yes. As of 10 September 2026, availability issues are reported in: Italy. Availability is national — a shortage in one country does not mean it is short everywhere.

Are there alternatives to Atovaquone + proguanil cloridrato?

2 of the active register entries indicate alternatives or equivalents (same active substance or an alternative treatment). Do not switch on your own — a pharmacist or prescriber can confirm the right substitute in your country.

Where does this Atovaquone + proguanil cloridrato availability data come from?

Directly from the official medicines-agency register that lists Atovaquone + proguanil cloridrato: AIFA (Italy). Every row on this page links to the underlying official record, and the dataset is refreshed from the primary sources every morning. Cross-language matching groups the same active substance across registers, so national spellings all resolve to this page.

Embed this tracker

Pharmacies, patient sites and newsrooms are welcome to embed the live status of Atovaquone + proguanil cloridrato — free, with attribution. Copy this snippet:

<iframe src="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/atovaquone-proguanil-cloridrato/embed.html" width="100%" height="150" loading="lazy" style="border:1px solid #e1e0d9;border-radius:12px" title="Atovaquone + proguanil cloridrato availability in Europe"></iframe>
<p style="font-size:12px">Source: <a href="https://www.mobidoctor.eu/medicine-shortages/medicine-shortages/atovaquone-proguanil-cloridrato/">Atovaquone + proguanil cloridrato shortage status — European Medicine Shortage Tracker</a> by MobiDoctor</p>
Cite: “Atovaquone + proguanil cloridrato: availability status across 1 European registers — European Medicine Shortage Tracker (MobiDoctor), 10 September 2026.” Link this page and the agency record. Statuses come from the linked official registers and can change daily.