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Hydroxychloroquine VS COVID-19

COVID-19 or coronavirus, the pandemic that has impacted the entire world, has become a subject for research and studies. These researches and studies are intended to detect the cure of this deadly virus. COVID-19 which has now taken lives of more than 100,000 people all over the world. Many scientists, scholars and medical experts are doing tests and researches over various drugs, that can be beneficial for treating this deadly disease.

One of these studies has examined a generic drug named Hydroxychloroquine, to be useful for treating coronavirus famed disease COVID-19. The brand name of Hydroxychloroquine is Plaquenil, which is highly popular as well. This drug is found to be sanctioned in 1955, by the FDA for treatment of immune-mediated ailments. Mostly used by dermatologists and rheumatologists, this drug is now being tested for utility in treating COVID-19.

Physicians use Hydroxychloroquine (Plaquenil), in combination with Azitromycin to offer relief against highly detrimental respiratory diseases like SARS-COVID-19. The drugs present antiviral symptoms, which is observed in vitro studies that are controllable as well as not controllable.

As per the results availed priorly, in the placebo-controlled trials, the patients are found to recover at a comparatively higher speed. Although the tested patients were mildly ill, and when the drug was added into the standard treatment procedure, the effects were found to be more helpful. Also, the study reflected that Hydroxychloroquine may prove to help reduce the severeness of the disease.

 

What Is Hydroxychloroquine (Plaquenil)?

 

Hydroxychloroquine which is sold by the brand name Plaquenil is an FDA approved drug, that is useful for the treatment of different types of malaria. This drug for treating malaria is taken into consideration when chloroquine has a sensitive effect over the concerned area. Although malaria is not the only disease, other than malaria, this drug can help in treating:

The drug is given in the form of pills, which can be taken via oral consumption. The drug consists of immune-mediated characters, that have made it a matter of research for COVID-19.

One can get Hydroxychloroquine (Plaquenil), to not cure, but to attain some sort of relief from the deadly disease caused by a coronavirus. As Europe is one of the major hotspots for the pandemic, it is highly recommended to avail the drug in the region. The authorities must get Hydroxychloroquine, Italy and other countries for a speedy recovery. The drug mainly identifies to the disease-modifying anti-rheumatic drugs, popular as DMARDs. The efficacy of the drug can be found as medicating skin-related issues found in lupus along with recovering swellings and aches caused in arthritis. However, the actual mechanism of the drug is not limited to treating the physical symptom of the disease.

As stated above as well, the US had approved Hydroxychloroquine for treating malaria in 1955. An also, the drug has its name mentioned in the WHO's List Of Essential Medicines. This list has several medicines and drugs that are highly effective and safe for the treatment of diseases found in the health system. The popularity of this medicine can be observed with the statistics of Most Prescribed Medicines in the United States. In 2017, it is the most prescribed medicine with over five million prescriptions and stands at 128th position. Here are a few more things, one must know before taking it for treatment.

  • One can use Hydrochloroquine (Plaquenil) for treating rheumatoid arthritis, erythematosus, systemic lupus along with few more autoimmune ailments.
  • Following the recent studies and examined effects of these drugs, the US Food and Drug Administration has authorized its use for urgent nursing for COVID-19.

 

Hydroxychloroquine (Plaquenil) Effects On COVID-19

As per the extracted results of independent pilot studies done so far, some antiviral properties are found in the drug, that is useful to cure the virus of COVID-19. The authorities have instructed medical professionals and patients that Hydroxychloroquine and chloroquine are restricted for medical trials and national emergency use programs, that are intended to treat COVID-19 only. Although, the results of the studies are not inclusive of confirming the efficacy of Hydroxychloriquine and chloroquine, as the data is not at all sound enough.

Following the emergent situation of COVID-19 pandemic, many countries like France, China and the USA have imposed secure protocols in terms of usage of these two drugs. A study has taken place in Wuhan, China, by Mr Zhan Zhang, who is the MD of Renmin Hospital along with his colleagues. The study involved 62 patients, who were prescribed Hydroxychloroquine and placebo, with a dose of 200 mg twice in 24 hours for the next 5 days. The treatment was continued along with the standard course of medication. The standard treatment includes oxygen therapy with few more unspecified regimens like antibacterial and antiviral agents. Also, the treatment consists of immunoglobulin, with or without corticosteroids. 

The data extracted showed that the prescribed treatment for 5 days with Hydroxychloroquine presented higher relief, followed by the less time of recovery in fever and cough.

How Does Hydroxychloroquine Work?

As Hydroxychloroquine is a known DMARD, it can regulate the immune system, that might react hyperactively, in some conditions. Physician's buy Hydroxychloroquine (Plaquenil) to modify the primary disease functions, in comparison to just influence the symptoms of the disease. As per the conventional functions of this drug, when a malarial parasite attacks red blood cells in a human body, the drug then averts it from breaking down haemoglobin in red blood cells. The number of parasites which can be prevented through Hydroxychloroquine is:

  • Plasmodium viva
  • P. ovale
  • P. malariae
  • Other susceptible tensity of P. falciparum.

Even, the hydroxychloroquine drug is efficient in curing inflammation that is triggered due to rheumatoid arthritis and lupus erythematosus.

In terms of COVID-19, the hydroxychloroquine drug will be able to obstruct the immune system from fervent attack over the virus. In Europe, a substantial number of patients had undergone organ failure, further causing death. The reason behind this is the continues attack by the immune system, which is prolonged, even after the virus is ineffective. The drug is useful as it helps in calming down the immune response, which reflects it's a utility in the treatment and further drives the government's to buy Hydroxychloroquine, Spain, Italy and other highly prone regions. It also states it's a utility in treating lupus, which is an autoimmune condition.

Although, the actual functions of Hydroxychloroquine and chloroquine for treating COVID-19 are yet unclear. Still, the drug seems to prevent coronavirus from attacking cells that were grown in the laboratory. Also, the scientists and experts are presently on the stage, where they will check the effectiveness of the drug on humans. As of now, the doses are also quite high for patients suffering from COVID-19.

Side Effects Of Hydroxychloroquine (Plaquenil)

The usage of Hydroxychloroquine and chloroquine for treating health conditions has been extended to an extended period, which is why it is assumed a safe medium for implementation. Although, there might be specific issues like stomach ache, vomiting, nausea, headache and sporadic cases of itchiness. 

However, there are certain health issues, that can occur like retinal harm to a few people, with overdose that too for an extended period. Also, the adults with health ailments like psoriasis, kidney ailments, heart arrhythmia and liver disease may find consequences of in-taking Hydroxychloroquine. Some of the general issues people face while using these medicines are:

 

These are mild effects and will get cured in a few days only. Other medicines will help in reducing the severeness of the symptoms or side effects.

 

Availability Of Hydroxychloroquine in the EU (Plaquenil) For COVID-19

The use of hydroxychloroquine/Plaquenil has been increased in hospitals of the entire world, following the findings in the early researches. Also, the FDA had issued Emergency Use Authorization on 28th, 2020, according to which the providers are allowed to appeal the suppliers to get Hydroxychloroquine (Plaquenil) for COVID-19 patients. Although, this doesn't mean that the FDA has permitted the medication to be used for curing COVID-19.

The patients are still advised to take doses as per the recommendation of doctors and their prescriptions. As the pandemic is increasingly escalating, people and governments are looking answer for how to get Hydroxychloroquine (Plaquenil)l, which has also reduced the supply of these medications. Another issue, prevailed is that, other than COVID-19 patients, the patients suffering from malaria and rheumatoid arthritis are also suffering a shortage of this medicine.

Following these two major issues, a very less number of suppliers have shown their response in this tragic time, and our partner pharmacy is one of those. With an extending supply of the Hydroxychloroquine in Europe, people can get Hydroxychloroquine, Italy, France, Spain, Sweden, Denmark and other major regions in Europe.

COVID-19, a major pandemic is required to be treated as soon as possible, following the detrimental effects on lives as well as economies. As Hydroxychloroquine is an efficient treatment source, people can take them in appropriate quantities and accordingly get healed with it.

DO NOT IN ANY WAY START A TREATMENT WITHOUT CONSULTING YOUR DOCTOR FOR A PRESCRIPTION AND THE CORRECT USAGE. AS WITH ANY OTHER MEDICINE, INCORRECT USE CAN HAVE SEVERE SIDE EFFECTS

 

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